Vaccines for Biodefense and Emerging and Neglected Diseases


  • Alan D.T. Barrett, Sealy Center for Vaccine Development, University of Texas at Galveston, USA
  • Lawrence Stanberry, College of Physicians and Surgeons, Columbia University, New York, USA

The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease.
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Primary: Researchers and physicians in vaccinology, virology, microbiology, parasitology and infectious diseases. Secondary: public health officials.


Book information

  • Published: December 2008
  • ISBN: 978-0-12-369408-9

Table of Contents

Agents of Emerging Infectious Diseases; Bacterial biothreats agents; Viral Biothreat agents; Vaccine Development Pathway; Immunology of Vaccines; Molecular Approches to Bacterial Vaccines; Viral Vectors; DNA Vaccines; Vaccine Adjuvants; Preclinical Vaccine Development; Vaccine Manufacturing; Clinical Trials of Vaccines; Pre-IND/IND Process; Regulatory Issues-USA; Special Issues around Veterinary Vaccines; Vaccines Misinformation; Vaccine for Military Application; Dengue; Filoviruses; Alphaviral Encephalitides; Foot & Mouth; Hantaviruses;Hepatitis; HIV; Human papillomavirus; Influenza; Japanese encephalitis; Junin & other Arenaviruses; Measles; Nipah and Hendra; O'Nyong, N'yong, and Chikungunya Viruses; Rabies; Ross River Virus; Rotavirus; SARS; Smallpox; Tick Borne Encephalitis; West Nile Virus; Yellow Fever; Anthrax; Brucellosis; Burkholderia mallei and Burkholderia pseudomallei; Chlamydia; Cholea; Botulinum; Erlichia; Extraintestinal pathogenic E. coli; Gonnorhea; Helicobactor pylori; Intestinal pathogenic E. coli; Lyme Disease; Niesseria meningitidis; Plague; Ricin-a toxin; Rickettsia; Salmonella; Shigella; Syphilis; Tuberculosis; Tularemia; African trypanosomiasis; Leishmaniasis; Leptospirosis; Malaria; Hookworm; Onchocerciasis; Schistosomiasis; American Trypanosomiasis