Understanding the Brain Through the Hippocampus

The Hippocampal Region as a Model for Studying Brain Structure and Function

Edited by

  • J. Storm-Mathisen
  • J. Zimmer
  • O.P. Ottersen

This high quality reference volume is the result of a number of up-to-date contributions selected on strict scientific criteria. Being of interest to neuroscientists in general, the work focusses on results heightening understanding of the structure and function of the CNS, whilst exploring the extent to which the findings made in the hippocampus can be extrapolated to other brain regions.The book has been compiled as a tribute to Professor Theodor W. Blackstad and his pioneering work on the anatomy of the hippocampal region. His outstanding contribution to science has undoubtedly influenced most of the many neuroscientists who today use the hippocampal region as a model in their research.
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Book information

  • Published: June 1990
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-81149-3


"This title...will be recognized immediately as a must reference work for hippocampologists..."

Table of Contents

Content Headings: Preface. A unique neuroanatomist and human being. (Haug et al). 1. Neurons, numbers and the hippocampal network. (D.G. Amaral, N.I. and B. Claiborne). 2. A quantitative comparison of the hippocampal subdivisions of diverse species including hedgehogs, laboratory rodents, wild mice, and men. (M.J. West). 3. Two different ways evolution makes neurons larger. (J.M. Bekkers and C.F. Stevens). 4. The subiculum. Cytoarchitectonically a simple structure, but hodologically complex. (M.P. Witter and H.J. Groenewegen). 5. Subicular projections to the hypothalamus and brain stem: Some novel aspects revealed in the rat by the anterograde Phaseolus vulgaris leukoagglutinin (PHA-L) tracing method. (C. Köhler). 6. Zinc-containing neurons in the hippocampus and related CNS structures. (C. Frederickson and G. Danscher). 7. Immunocytochemical demonstration of the calcium-binding proteins calbindin-D 28K and parvalbumin in the hippocampus and dentate area of the domestic pig. (I.E. Holm, F.A. Geneser, J. Zimmer and K.G. Baimbridge). 8. A quantitative electron microscopic immunocytochemical study of the distribution and synaptic handling of glutamate in rat hippocampus. (O.P. Ottersen, J. Storm-Mathisen, C. Bramham, R. Torp, J. Laake and V. Gundersen). 9. Regulation of glutamate and aspartate release from the Schaffer collaterals and other projections of hippocampal pyramidal cells. (J.V. Nadler, D. Martin, G.A. Bustos, S.P. Burke and M.A. Bowe). 10. Dendritic excitation by glutamate in CA1 hippocampal cells. (Ø. Hvalby). 11. Membrane currents in hippocampal neurons. (D.A. Brown, B.H. Gähwiler, W.H. Griffith, J.V. Halliwell). 12. Potassium currents in hippocampal pyramidal cells. (J.F. Storm). 13. Cytosolic free calcium in hippocampal CA3 pyramidal cells. (T. Knüpfel, S. Charpak, D.A. Brown and B.H. Gähwiler). 14. Activity dependent ionic changes and neuronal plasticity in rat hippocampus. (U. Heinemann, J. Stabel and G. Rausche). 15. Synaptic integration in hippocampal CA1 pyramids. (P. Andersen). 16. Long-term potentiation in the hippocampal CA1 region: its induction and early temporal development. (B. Gustafsson and H. Wigström). 17. The natures and causes of hippocampal long-term potentiation. (G.S. Lynch, M. Kessler, A. Arai and J. Larsen). 18. Increases in glutamate release and phosphoionositide metabolism associated with long-term potentiation and classical conditioning. (M.A. Lynch, M.L. Errington, M.P. Clements, T.V.P. Bliss, C.R.-D. Negro and S. Laroche). 19. Spatial organization of physiological activity in the hippocampal region: relevance to memory formation. (G. Buzsáki, L.S. Chen and F.H. Gage). 20. Similarities in circuitry between Ammon's horn and dentate gyrus: local interactions and parallel processing. (P.A. Schwartzkroin, H.E. Scharfman and Robert S. Sloviter). 21. Comparison of spatial and temporal characteristics of neuronal activity in sequential stages of hippocampal processing. (C.A. Barnes, B.L. McNaughton, S.J.Z. Mizumori, B.W. Leonard and L.-H. Lin). 22. A computational theory of the hippocampal cognitive map. (J. O'Keefe). 23. GABAergic mechanisms in the CA3 hippocampal region during early postnatal life. (Y. Ben-Ari. C, Rovira, J.L. Gaiarsa, R. Corradetti, O. Robain and E. Cherubini). 24. Plasticity of identified neurons in slice cultures of hippocampus: a combined Golgi/electronmicroscopic and immunocytochemical study. (M. Frotscher, B. Heimrich and H. Schwegler). 25. Growth factors and growth factor receptors in the hippocampus: Role in plasticity and response to injury. (M. Nieto-Sampedro and O. Boloventa). 26. NGF dependent sprouting and regeneration in the hippocampus. (F.H. Gage, G. Buszáki and D. Armstrong). 27. Seizures, neuropeptide regulation and mRNA expression in the hippocampus. (C.M. Gall, J. Lauterborn, P. Isackson and J. White). 28. Grafting of fetal CA3 neurons to excitotoxic, axon-sparing lesions of the hippocampal CA3 area in adult rats. (N. Tønder, T. Søronsen and J. Zimmer). 29. Reafferentation of the subcortically denervated hippocampus as a model for transplant-induced functional recovery in the CNS. (A. Björklund, O.G. Nilsson and P. Kalén). 30. Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms? (C.W. Cotman, J.W. Geddes and J.S. Kahle). 31. Hippocampal formation: Anatomy and the patterns of pathology in Alzheimer's disease. (G.W. Van Hoesen and B.T. Hyman). Subject index.Imprint: Amsterdam