Understanding Pathogen Behaviour

Virulence, Stress Response and Resistance

Pathogens respond dynamically to their environment. Understanding their behaviour is critical both because of evidence of increased resistance to established sanitation and preservation techniques, and because of the increased use of minimal processing technologies which are more vulnerable to the development of resistance. Understanding pathogen behaviour summarises the wealth of recent research and its implications for the food industry.

After two introductory chapters on ways of analysing and modelling pathogens, Part one summarises current research on what determines pathogenicity, stress response, adaptation and resistance. Part two reviews the behaviour of particular pathogens, reviewing virulence, stress response and resistance mechanisms in such pathogens as Salmonella, E.coli and Campylobacter. The final part of the book assesses how pathogens react and adapt to particular stresses from heat treatment and the effects of low temperature to the use of disinfectants and sanitisers.

With its distinguished editor and international team of contributors, Understanding pathogen behaviour is a standard reference for the food industry in ensuring food safety.
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Those in the food industry in charge of ensuring food safety


Book information

  • Published: July 2005
  • Imprint: Woodhead Publishing
  • ISBN: 978-1-85573-953-6


…an essential resource for all in the food safety industry. …a must-have microbiology text, dealing with prevailing issues in the food safety industry worldwide., Food Processing
…a well written book containing a wealth of up-to-date information., Microbiology Today 2006
…highly recommended to food scientists and, especially, to practical workers in the food industry, who are responsible for ensuring food safety., Advances in Food Science

Table of Contents

Part 1 Understanding virulence, stress response and resistance mechanisms: Understanding the behaviour of pathogenic cells: Proteome and metabolome analysis; Mechanistic modelling of pathogen stress response; The development of pathogenicity; Host-pathogen interactions; Factors affecting stress response; Cross-protective effects of bacterial stress; Sublethal injury, pathogen virulence and adaptation; Detecting sublethally-damaged cells. Part 2 Virulence and stress response mechanisms of particular pathogens: Salmonella: Virulence, stress response and resistance; E.coli: Virulence, stress response and resistance; Campylobacter: Stress response and resistance; Bacillus cereus: Factors affecting virulence; Staphylococcus aureus: Pathogenesis and stress response; Vibrio species: Pathogenesis and stress response. Part 3 Pathogen resistance and adaptation to particular stresses: Understanding pathogen survival and resistance in the food chain; Pathogen resistance and adaptation to heat stress; Pathogen resistance and adaptation to emerging technologies; Pathogen resistance and adaptation to natural antimicrobials; Pathogen resistance and adaptation to disinfectants and sanitisers; Pathogen resistance and adaptation to low temperature. Part 4 Appendix: Clostridium; Quorum sensing.