Transplantation of the Liver book cover

Transplantation of the Liver

Spearheaded by two of the world's preeminent experts in liver surgery, the new edition of this landmark masterwork encompasses all of today's best knowledge in the field. It provides detailed discussions of everything from pathophysiology and patient and donor selection...through transplantation anesthesia and full range of operative immunosuppression, postoperative care, and ethical issues. The result is an ideal single source for authoritative, up-to-the-minute guidance on every imaginable aspect of liver transplantation.

Liver Transplantation Specialists and Fellows, General Surgeons, Liver Specialists, Gastroenterologists, and Health Science Libraries.


Published: July 2005

Imprint: Saunders

ISBN: 978-0-7216-0118-2


  • I. General Considerations

    1. History of Liver and Other Splanchnic Organ Transplantation
    2. Liver Organ Allocation: The U.S. Model
    3. Liver Organ Allocation: The Great Britain and European Models
    4. Hepatic Anatomy
    5. Hepatic Physiology and Assessment of Hepatic Function
    6. Molecular Biology of the Liver
    7. Influence of Liver Transplantation on Liver Surgery

    II. Patient Evaluation: Adult

    8. Current Indications, Contraindications and Timing for Liver Transplantation
    9. Transplantation for Viral Hepatitis A & B
    10. Transplantation for Hepatitis C
    11. Transplantation for Fulminant Hepatic Failure
    12. Transplantation for Primary Biliary Cirrhosis
    13. Transplantation for Sclerosing Cholangitis
    14. Liver Transplantation for Autoimmune Chronic Active Hepatitis
    15. Transplantation for Primary Hepatic Malignancy
    16. Liver Transplantation for Metastatic Hepatic Malignancy
    17. Liver Transplantation for Hematological Disorders: Hereditary Hemochromatosis, Protophyria, and Coagulation Defects
    18. Transplantation for Budd-Chiari Syndrome
    19. Liver Transplantation for Alcoholic Cirrhosis
    20. Unusual Indications for Liver Transplantation

    III. Patient Evaluation: Pediatric

    21. General Criteria for Pediatric Transplantation
    22. Transplantation for Cholestatic Liver Disease
    23. Transplantation for Biliary Atresia
    24. Liver Transplantation for Metabolic Disease
    25. Transplantation for Hepatic Malignancy in Children
    26. Nutritional Aspects of Pediatric Liver Transplantation

    IV. Special Considerations in Patient Evaluation

    27. Ethical Decisions in Liver Transplantation
    28. Psychosocial Assessment of Adult Liver Transplant Recipients
    29. Pretransplantation Evaluation: Pulmonary, Cardiac, and Renal
    30. Pretransplantation Infectious Disease Screening for Transplantation Candidates
    31. Role of the Clinical Nurse Coordinator: Preoperative Care
    32. Radiologic Evaluation in the Liver Trnaplant Patient
    33. Monitoring and Care of the Patient Prior to Transplantation
    34. Nutritional Aspects of Adult Liver Transplantation
    35. Surgery for Portal Hypertension in the Era of Liver Transplantation

    V. The Operation

    36. Donor Selection and Management
    37. The Donor Operation
    38. Principles of Organ Preservation
    39. The Recipient Hepatectomy and Grafting
    40. Anesthesia for Liver Transplantation

    VI. Split and Living Donor Transplantation

    41. Split Liver Transplantation for the Pediatric and Adult Recipient
    42. Living Related Liver Transplantation in Pediatric Recipients
    43. Split Liver Transplantation for Two Adults
    44. Adult Living Donor and Recipient Evaluation and Selection
    45. Adult Living Donor Hepatectomy and Recipient Operation
    46. Imaging Techniques in Living Donor Transplantation
    47. Outcomes in Living Donor Transplantation

    VII. Unusual Operative Problems

    48. Venous Anomalies Including Protal Vein Thrombosis and Prior Portosystemic Shunts
    49. Liver Transplantation and Situs Inversus
    50. Retransplantation
    51. Clinical Management of Necrotic Liver During Transplantation Surgery
    52. Transplantation of the Liver With Digestive Organs
    53. Combined Liver-Kidney Transplantation
    54. Auxiliary Transplants

    VIII. Postoperative Care

    55. Postoperative Intensive Care Management
    56. Postoperative Intensive Care Management: Children
    57. Postoperative Care Management: Adults
    58. Postoperative Care Management: Children
    59. Renal Failure in the Adult Transplant Recipient
    60. Graft Failure: Cause, Etiology, Recognition and Treatment
    61. Technical Problems: Biliary
    62. Technical Problems: Vascular
    63. Infections After Liver Transplantation
    64. Late Onset Complications and Recurrent Non-Malignant Disease
    65. Neuropsychiatric Outcomes in Liver Transplantation
    66. Transplantation of the Liver: Postoperative Neurological Disorders and Prognosis
    67. Role of the Posttransplantation Coordinator

    IX. Liver Transplant Pathology

    68. Histological Patterns of Rejection and Other Causes of Liver Dysfunction
    69. Pathology of Recurrence of Non-Neoplastic Disease After Liver Transplantation
    70. Posttransplantation De Novo Malignancies

    X. Immunology of Liver Transplantation

    71. Rejection After Transplantation
    72. Cell Migration, Chimerism, and Graft Acceptance, With Particular Reference To the Liver
    73. ABO, Tissue Typing, and Crossmatching Incompatibility in Liver Transplantation

    XI. Immunosuppression

    74. Induction and Maintenance of Immunosuppression
    75. Special Considerations for Pediatric Immunosuppression After Liver Transplantation
    76. Treatment of Acute and Chronic Rejection
    77. New Immunosuppressive Drugs

    XII. Survival and Results

    78. Preoperative Predictors of Outcome in Liver Transplantation: Models for Defining High-Risk Recipients
    79. Overall National Results of Liver Transplantation Between 1987 and 2000
    80. Long-Term Functional Recovery and Quality of Life
    81. Results: Survival and Quality of Life After Orthotopic Liver Transplantation in Children

    XIII. Future Developments in Liver Transplantation

    82. Gene Therapy in Transplantation
    83. Xenotransplantation
    84. Hepatocyte Transplantation
    85. New Approaches in Immunosuppression
    86. Ischemia Reperfusion Injury of the Liver
    87. Extracorporeal Xenogeneic Liver Support
    88. Development of Bio Artificial Liver


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