Translational Endocrinology of Bone
Reproduction, Metabolism, and the Central Nervous System
Edited by- Gerard Karsenty, Professor and Chair, Department of Genetics and Development, Columbia University Medical School, New York, NY, USA
The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology.
Hardbound, 236 Pages
Published: October 2012
Imprint: Academic Press
ISBN: 978-0-12-415784-2
Contents
1. Introduction
2. Bone Remodelling & Regulation*
3. Food Intake of Bone Formation
4. Central Control of Bone Mass5. Neuropeptide Y and Bone Formation
6. Gut Serotonin Bone Formation
6. Serotonin: The Central Link between Bone Mass and Energy Metabolism7. Gut Serotonin and Osteoporosis
8. Regulation of Bone Resoprtion by PPARGamma10. Regulation of Energy Metabolism by Bone
11. Bone Marrow Fat and Bone Mass12. Bone Mass and Energy Metabolism in Humans
13. Regulation of Fertility by Bone14. Molecular Signaling by Osteocalcin
15. Regulation of Phosphate Metabolism by FGF2316. The Clinical Use of FGF 23
17. Transcriptional Regulation of the Endocrine Function of Bone
