Translation of Addictions Science Into Practice

Edited by

  • Peter Miller, Medical University of South Carolina, Charleston, USA
  • David Kavanagh, Royal Brisbane Hospital, School of Medicine, University of Queensland, AUSTRALIA

Recent advances in the understanding of the genetic, neurochemical, behavioral and cultural underpinnings of addiction have led to rapid advances in the understanding of addiction as a disease. In fact, advances in basic science and the development of new pharmacological and behavioral therapies associated with them are appearing faster than can be assimilated not only by clinical researchers but practitioners and policy makers as well. Translation of science-based addictions knowledge into improved prevention, assessment and treatment, and communication of these changes to researchers and practitioners are significant challenges to the field.The general aim of this book is to summarize current and potential linkages between advances in addiction science and innovations in clinical practice. Whilst this book is primarily focused on translation, it also encompasses some scientific advances that are relevant to dissemination, and the book is itself a tool for disseminating innovative thinking.The goal is to generate interest in application opportunities from both recent research and theoretical advances.
View full description


Researchers in addiction, academic clinical researchers in addiction, practitioners and policy makers who are committed to a scientist-practitioner model and are interested in advances in their field.


Book information

  • Published: May 2007
  • Imprint: PERGAMON
  • ISBN: 978-0-08-044927-2

Table of Contents

TRANSLATION OF ADDICTIONS SCIENCE INTO PRACTICE: UPDATE AND FUTURE DIRECTIONSPeter M. Miller and David J. KavanaghList of ContributorsPrefaceSECTION I: GENETICS AND NEUROSCIENCEChapter 1The Interplay between Genotype and Gene Expression in Human Brain: What Can It Teach Us about Alcohol Dependence? (Dodd)Chapter 2Common Genetic Influences on Antisociality and Addictions: Implications for Clinical Science and Practice (King)Chapter 3Opioids, Pain and Addiction: Cause and Consequence (White and Hay)Chapter 4Imbalance between Neuroexcitatory and Neuroinhibitory Amino Acids Causes Craving for Ethanol: From Animal to Human Studies (DeWitte)Chapter 5Cannabis and the Brain: Implications of Recent Research (Sundram and Castle)SECTION II. PHARMACOTHERAPYChapter 6The Plasticity of Alcohol Addiction Suggests Novel Approaches to Pharmacological Intervention (Mulholland And Chandler)Chapter 7Pharmacotherapies for the Treatment of Alcohol Dependence: Current and on the Horizon (Wright, Baros, Anton)Chapter 8Agonist Treatment for Stimulant Abuse and Dependence(Herin and Grabowski)Chapter 9Topiramate-Induced Neuromodulation of Cortico-Mesolimbic Dopamine: Implications for the Treatment of Nicotine and Alcohol Dependence (Johnson)SECTION III. PSYCHOLOGY AND SOCIOLOGYChapter 10Advances in the Scientific Study of Craving for Alcohol and Tobacco (MacKillop and Monti)Chapter 11Advances in the Treatment of Craving for Alcohol and Tobacco (Monti and MacKillop)Chapter 12Cognitive, Affective and Motivational Effects of Smoking (Powell and Dawkins)Chapter 13Therapeutic Outcome Research and Dissemination of Empirically Based Treatment for Alcohol Use Disorders (Wilbourne)Chapter 14Implications of Research on Comorbidity for the Nature and Management of Substance Misuse(Mueser, Kavanagh, & Brunette)Chapter 15The Role of Impulsive Personality Traits in the Initiation, Development and Treatment of Substance Misuse Problems (Dawe, Loxton, Gullo, Staiger, Kambouropoulos, Perdon, and Wood)Chapter 16Translational Research Involving Adolescent Substance Abuse (Cornelius and Clark)SECTION IV: PRACTICE AND POLICYChapter 17Dissemination of Evidence-Based Treatment into Substance Abuse Clinical Practice (Sorensen, Hettema, and Chen)Chapter 18Alcohol Screening and Intervention in Medical and Surgical Settings (Stewart and Miller)Chapter 19Internet-Based Interventions for Alcohol, Tobacco and Other Substances of Abuse (Cunningham)Chapter 20Alcohol Use among Undergraduate Students: From Brief Interventions to Behavioral Economics (Henslee, Irons, and Correia)Chapter 21Ethical and Policy Issues in the Translation of Genetic and Neuroscience Research on Addiction (Carter and Hall)SECTION V: CONCLUSIONChapter 22Pathways to Innovation in Addiction Practice (Kavanagh and Miller)Subject Index