Transduction Mechanisms in Cellular Signaling book cover

Transduction Mechanisms in Cellular Signaling

Cell Signaling Collection

Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.


Researchers and graduate students in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, Molecular and Cellular Physiology, Pharmacy, and Biomedical Sciences.

Paperback, 610 Pages

Published: April 2011

Imprint: Academic Press

ISBN: 978-0-12-383862-9


  • Volume two includes 183 chapters divided in 8 sections, including:

    Section A: Protein Phosphorylation

    56 Eukaryotic Kinomes: Genomics and Evolution of Protein Kinases

    57 Modular Protein Interaction Domains in Cellular Communication

    58 Structures of Serine/Threonine and Tyrosine Kinases

    59 Protein Tyrosine Kinase Receptor Signaling Overview

    60 Signaling by the Platelet-Derived Growth Factor Receptor Family

    61 The Epidermal Growth Factor Receptor Family

    62 Mechanisms and Functions of Eph Receptor Signaling

    63 Cytokine Receptor Signaling

    64 The Negative Regulation of JAK/STAT signaling

    65 Protein Kinase Inhibitors

    66 Integrin Signaling: Cell Migration, Proliferation, and Survival

    67 Downstream Signaling Pathways: Modular Interactions

    68 Non-Receptor Tyrosine Kinases in T Cell Antigen Receptor Function

    69 Receptor Tyrosine Kinase Signaling and Ubiquitination

    70 TGFb Signal Transduction

    71 Mitogen-Activated Protein Kinases

    72 Recognition of Phospho-Serine/Threonine Phosphorylated Proteins

    73 AMP-Activated Protein Kinase

    74 Principles of Kinase Regulation

    75 Calcium/Calmodulin-Dependent Protein Kinase II

    76 Glycogen Synthase Kinase 3

    77 The PIKK Family of Protein Kinases

    78 Histidine Kinases in Two-Component Signaling Pathways

    79 The EF2K/MHCK/TRPM7 Family of Atypical Protein Kinases

    80 The Leucine-Rich Repeat Receptor Protein Kinases of Arabidopsis thaliana

    81 Engineering Protein Kinases with Specificity for Unnatural Nucleotides and Inhibitors

    82 Clinical Applications of Kinase Inhibitors in Solid Tumors

    83 Ubiquitin-Mediated Regulation of Protein Kinases in NFκB Signaling

    84 Global Analysis of Phosphoregulatory Networks

    Section B: Protein Dephosphorylation

    85 Phosphatase Families Dephosphorylating Serine and Threonine Residues in Proteins

    86 The Structure and Topology of Protein Serine/Threonine Phosphatases

    87 Naturally Occurring Inhibitors of Protein Serine/Threonine Phosphatases

    88 Protein Phosphatase 1 Binding Proteins

    89 Protein Serine/Threonine Phosphatase Inhibitors and Human Disease

    90 Calcineurin

    91 Protein Serine/Threonine-Phosphatase 2C (PP2C)

    92 Approaches to the Identification of Protein Tyrosine Phosphatase Substrates

    93 Inhibitors of Protein Tyrosine Phosphatases

    94 Regulating Receptor PTP Activity

    95 CD45


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