Transduction Mechanisms in Cellular Signaling
Cell Signaling Collection
Edited by- Edward A. Dennis, Department of Chemistry and Biochemistry and Department of Pharmacology in the School of Medicine at the University of California, San Diego
- Ralph A. Bradshaw, Department of Chemistry and Pharmaceutical Chemistry; and Mass Spectrometry Facility, University of California, San Francisco, Department of Physiology and Biophysics, College of Medicine, University of California, Irvine, Irvine, CA.
Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.
Paperback, 610 Pages
Published: April 2011
Imprint: Academic Press
ISBN: 978-0-12-383862-9
Contents
Volume two includes 183 chapters divided in 8 sections, including:
Section A: Protein Phosphorylation
56 Eukaryotic Kinomes: Genomics and Evolution of Protein Kinases
57 Modular Protein Interaction Domains in Cellular Communication58 Structures of Serine/Threonine and Tyrosine Kinases
59 Protein Tyrosine Kinase Receptor Signaling Overview60 Signaling by the Platelet-Derived Growth Factor Receptor Family
61 The Epidermal Growth Factor Receptor Family62 Mechanisms and Functions of Eph Receptor Signaling
63 Cytokine Receptor Signaling64 The Negative Regulation of JAK/STAT signaling
65 Protein Kinase Inhibitors66 Integrin Signaling: Cell Migration, Proliferation, and Survival
67 Downstream Signaling Pathways: Modular Interactions68 Non-Receptor Tyrosine Kinases in T Cell Antigen Receptor Function
69 Receptor Tyrosine Kinase Signaling and Ubiquitination70 TGFb Signal Transduction
71 Mitogen-Activated Protein Kinases72 Recognition of Phospho-Serine/Threonine Phosphorylated Proteins
73 AMP-Activated Protein Kinase74 Principles of Kinase Regulation
75 Calcium/Calmodulin-Dependent Protein Kinase II76 Glycogen Synthase Kinase 3
77 The PIKK Family of Protein Kinases78 Histidine Kinases in Two-Component Signaling Pathways
79 The EF2K/MHCK/TRPM7 Family of Atypical Protein Kinases80 The Leucine-Rich Repeat Receptor Protein Kinases of Arabidopsis thaliana
81 Engineering Protein Kinases with Specificity for Unnatural Nucleotides and Inhibitors82 Clinical Applications of Kinase Inhibitors in Solid Tumors
83 Ubiquitin-Mediated Regulation of Protein Kinases in NF¿B Signaling84 Global Analysis of Phosphoregulatory Networks
Section B: Protein Dephosphorylation85 Phosphatase Families Dephosphorylating Serine and Threonine Residues in Proteins
86 The Structure and Topology of Protein Serine/Threonine Phosphatases87 Naturally Occurring Inhibitors of Protein Serine/Threonine Phosphatases
88 Protein Phosphatase 1 Binding Proteins89 Protein Serine/Threonine Phosphatase Inhibitors and Human Disease
90 Calcineurin91 Protein Serine/Threonine-Phosphatase 2C (PP2C)
92 Approaches to the Identification of Protein Tyrosine Phosphatase Substrates93 Inhibitors of Protein Tyrosine Phosphatases
94 Regulating Receptor PTP Activity95 CD45
