Toxicology Handbook
By- Frank Daly, MBBS, FACEM, Consultant Clinical Toxicologist, Emergency Physician and Director of Clinical Service Redesign, Royal Perth Hospital; Professor in Emergency Medicine; University of Western Australia; Consultant Clinical Toxicologist, WA and NSW Poisons Information Centres, Australia
- Mark Little, MBBS, DTM&H(Lond), FACEM, MPH&T IDHA, Consultant Emergency Physician and Clinical Toxicologist, Royal Perth Hospital; Clinical Senior Lecturer in Emergency Medicine, University of Western Australia; Consultant Clinical Toxicologist, WA and NSW Poisons Information Centres, Australia
- Mike Cadogan, MA(Oxon), MBChB, FACEM, Consultant Emergency Physician, Sir Charles Gairdner Emergency Department, Clinical Senior Lecturer in Emergency Medicine, University of Western Australia, Australia
- Lindsay Murray, MB, BS, FACEM, Consultant Emergency Physician and Clinical Toxicologist, Sir Charles Gairdner Hospital, Perth, WA; Clinical Associate Professor of Emergency Medicine, University of Western Australia
An updated guide to the approach, assessment and management of poisoned patients
Poisoning is a common emergency department presentation, and is the third major cause of hospital admission in Australia.
The new edition of this all-encompassing toxicology reference describes the risk assessment-based approach pioneered by its principal authors.
It also deals with specific toxicology considerations like alcohol abuse, dependence and withdrawal, and poisoning in children and the elderly. Important locally relevant information on bites, stings and envenoming is also included.
The concise layout of this didactic medical guide enables readers to quickly locate required information - essential in a poisoning emergency.
Established as a primary reference in Australian Poisons Information Centres, the
Paperback, 529 Pages
Published: December 2010
Imprint: Churchill Livingstone
ISBN: 978-0-7295-3939-5
Contents
- Section 1: Introduction
- Who are the authors
- Scope of the book
- Handbook of acute management of common poisonings.
- Hands on and practical approach.
- Rationale for drugs included
- How to use the book
- Universal disclaimer
- Overview of approach to toxicology/toxinology
- Principles of risk assessment-based approach
- Resuscitation, Risk assessment, Supportive care, Decontamination, Investigations, Enhanced elimination, Antidotes, Disposition
- Approach to special problems: Approach to snakebite, mushroom poisoning, plant poisoning
- Toxidromes: Serotonin syndrome, Neuroleptic Malignant Syndrome, anticholinergic syndrome, cholinergic syndrome
- Important poisoning manifestations and management: Seizures, coma, hypotension, delirium and agitation
- Drugs of abuse and withdrawal syndromes: Alcohol, amphetamines, opiods, sedative hypnotics, body packers and stuffers
- Investigations: Laboratory results: acidosis, anion gap and osmolar gap, recommended baseline investigations with interpretation. Unit conversion table: ECG interpretation in poisoning: Radiology.
- Special populations: Paediatric poisoning: 1 tablet can kill (list), special precautions in management (overnight stay, paracetamol, risk of charcoal etc); Pregnancy and lactation and poisoning; and Geriatric poisoning
- Approach to diagnosis, investigation and management of the poisoned patient with all of the common drug presentations. Updated with 8 new drug chapters as per readers nominations and feedback
- Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antidotes. New chapter on Intralipid, the latest development in antidote therapy
- Approach to snakebite, spider and marine envenoming. New chapter on tick envenoming
- Detailed description of indications, contraindications, clinical administration and therapeutic end-points for all antivenoms

