Toxicogenomics-Based Cellular Models
Alternatives to Animal Testing for Safety Assessment
- Jos Kleinjans, Professor and Chair, Department of Toxicogenomics, Maastricht University, the Netherlands
Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores âomics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.
Scientists, academics and students within the fields of toxicology and molecular biology, as well as regulatory authorities involved in chemical safety