The Unfolded Protein Response and Cellular Stress, Part B

Edited by

  • P. Michael Conn, Texas Tech University Health Sciences Center, Lubbock, USA

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.
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Researchers and students in cell, molecular and developmental biology


Book information

  • Published: February 2011
  • ISBN: 978-0-12-385114-7

Table of Contents

Section I: Measuring and Modifying the UPR

  1. Methods for investigating the UPR in filamentous fungi
  2. Thomas Guillemette, Arthur F.J. Ram, Neuza D.S.P. Carvalho, Aymeric Joubert, Philippe Simoneau, David B. Archer

  3. Assays for detecting the unfolded protein response
  4. Karen Cawley, Shane Deegan, Afshin Samali, Sanjeev Gupta

  5. Analysis of the role of nerve growth factor in promoting cell survival during endoplasmic reticulum stress in PC12 cells
  6. Koji Shimoke , Harue Sasaya, and Toshihiko Ikeuchi

  7. Measuring ER stress and the unfolded protein response using mammalian tissue culture system
  8. Christine M. Oslowski and Fumihiko Urano

  9. Real-Time Monitoring of Er Stress in Living Cells And Animals Using Estrap Assay
  10. Masanori Kitamura and Nobuhiko Hiramatsu

  11. HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells
  12. Huiping Zhou

  13. Dexamethasone induction of a heat-stress response
  14. José A. Guerrero, Vicente Vicente, Javier Corral

  15. Detecting and Quantitating Physiological Endoplasmic Reticulum Stress
  16. Ling Qi, Liu Yang and Hui Chen

    Section II: Molecular Components of the UPR

  17. PI 3-Kinase Regulatory Subunits as Regulators of the Unfolded Protein Response
  18. Jonathon N. Winnay and C. Ronald Kahn

  19. The Emerging Role of Histone Deacetylases (HDACs) in UPR regulation
  20. Soumen Kahali, Bhaswati Sarcar & Prakash Chinnaiyan

  21. Immunohistochemical detection of Activating Transcription Factor 3, a hub of the cellular adaptive-response network
  22. Tsonwin Hai, Swati Jalgaonkar, Christopher C. Wolford, and Xin Yin

  23. Experimental approaches for elucidation of stress-sensing mechanisms of the Ire1 family proteins
  24. Daisuke Oikawa and Yukio Kimata

  25. Measurement and Modification of the Expression Level of the Chaperone Protein and Signaling Regulator GRP78/BiP in Mammalian Cells
  26. Wan-Ting Chen and Amy S. Lee

  27. The Endoplasmic Reticulum associated degradation and disulfide reductase ERdj5
  28. Ryo Ushioda and Kazuhiro Nagata

  29. Structural Insight into the Protective Role of P58(IPK) during Unfolded Protein Response
  30. Jiahui Tao, Bingdong Sha

  31. Principles of IRE1 modulation using chemical tools
  32. Kenneth P. K. Lee and Frank Sicheri

  33. Methods to study stromal-cell derived factor 2 in the context of ER stress and the unfolded protein response in Arabidopsis thaliana
  34. Andrea Schott & Sabine Strahl

  35. Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase
  36. Joachim D. Uys, Ying Xiong, and Danyelle M. Townsend

  37. Methods for Analyzing eIF2 Kinases and Translational Control in the Unfolded Protein Response

Brian F. Teske, Thomas D. Baird, and Ronald C. Wek