The Pancreatic Beta Cell

Series Editor:

  • Gerald Litwack, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press.

The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones.  A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed.

This volume focuses on the pancreatic beta cell.

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Researchers, faculty, and graduate students interested in cutting-edge review concerning the molecular and cellular biology of vitamins, hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry, molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested.


Book information

  • Published: February 2014
  • ISBN: 978-0-12-800174-5

Table of Contents

  1. Metabolic Regulation of Insulin Secretion
    Kevin Keane and Philip Newsholme
  2. Proinsulin Entry and Transit through the Endoplasmic Reticulum in Pancreatic Beta Cells
    Ming Liu, Jordan Wright, Huan Guo, Yi Xiong and Peter Arvan
  3. Metabolism-Secretion Coupling and Mitochondrial Calcium Activities in Clonal Pancreatic Beta-Cells
    Lukas N. Groschner, Muhammad Rizwan Alam and Wolfgang F. Graier
  4. Metabolic Syndrome and Ionic Channels in Pancreatic Beta-Cells
    Marcia Hiriart, Myrian Velasco, Carlos Larqué and Carlos Manlio Diaz-Garcia
  5. The Beta Cell Immunopeptidome
    Nadine L. Dudek and Anthony W. Purcell
  6. Autophagy and Pancreatic Beta Cells
    Simona Mazza and Tania Maffucci
  7. The Somatostatin Receptor in Human Pancreatic β-Cells
    Matthias Braun
  8. Modulation of the Pancreatic Islet-Stress Axis as a Novel Potential Therapeutic Target in Diabetes Mellitus
    Barbara Ludwig, Andreas Barthel, Andreas Reichel, Norman L. Block, Stefan Ludwig, Andrew V. Schally and Stefan R. Bornstein
  9. Regenerative Medicine for Diabetes: Differentiation of Human Pluripotent Stem Cells into Functional β Cells in Vitro and their Proposed Journey to Clinical Translation
    Bipasha Bose, Kishore Reddy Katikireddy and Sudheer Shenoy
  10. The Calcium-Sensing Receptor and β-Cell Function
    Paul E. Squires, Peter M. Jones, Mustafa Y.G. Younis and Claire E. Hills
  11. Cellular Inhibitor of Apoptosis Protein-1 and Survival of Beta Cells Undergoing Endoplasmic Reticulum Stress
    Pu Xia and Yanfei Qi 
  12. β-Cell Responses to Nitric Oxide
    Katarzyna A. Broniowska, Bryndon J. Oleson and John A. Corbett
  13. Activated Protein C and its Potential Applications in prevention of islet β Cell Damage and Diabetes
    Meilang Xue and Christopher J. Jackson
  14. Zinc and its Transporters, Pancreatic β-Cells, and Insulin Metabolism
    Liping Huang
  15. The NOTCH Pathway in β-Cell Growth and Differentiation
    Yael Bar and Shimon Efrat
  16. Roles of HNF1α and HNF4α in Pancreatic β-Cells: Lessons from a Monogenic form of Diabetes (MODY)
    Kazuya Yamagata
  17. Role of the Mammalian Target of Rapamycin (mTOR) Complexes in Pancreatic Beta Cell Mass Regulation
    Alberto Bartolome and Carlos Guillén