The Ovary

Edited by

  • Peter Leung, University of British Columbia, Vancouver, British Columbia, Canada
  • Eli Adashi, University of Utah, Salt Lake City, Utah, U.S.A.

This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade. It looks at ovarian function from a detailed molecular and cellular level. The updated chapters, along with the new material, represent an unparalleled compilation of chapters relevant to contemporary ovarian physiology. The book is divided into 8 sections: The Ovarian Follicular Apparatus: Operational Characteristics; Oocyte Maturation and Ovulation; The Corpus Luteum; Putative Intraovarian Regulators; Cyclic Ovarian Cell Death; Novel Experimental Models; Human Ovarian Pathophysiology: Select Aspects; and Human Ovarian Surface Epithelium and Neoplasia.
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Reproductive endocrinologists, physiologists, cell and molecular biologists, fertility/infertility specialists, as well as obstetriticans and gynocologists.


Book information

  • Published: December 2003
  • ISBN: 978-0-12-444562-8


"The chapters are well written...The Ovary should be of great value to established scholars in the field because it conveniently reviews the developments of the past decade and will quickly bring them up to date. This handsome volume can be highly recommended. Each chapter is amply referenced, making this book a great resource for anyone with a detailed interest in the ovary." -TRENDS IN ENDOCRINOLOGY AND METABOLISM, SEPTEMBER 2004 "...a comprehensive reference and value for the money...more for those who are curious to enquire into the scientific basis of clinical medicine." --David T. Baird, MB BChr, DSc, Professor Emeritus, University Department of Obstetrics and Gynaecology and Director ofo Contraceptive Development Network, Edinburgh, UK for Journal of Family Planning and Reproductive Health Care, Vol. 31, No. 1 June 20052004

Table of Contents

Neural and Neurotrophic Control of Ovarian DevelopmentDynamics of Human Follicular Growth: Morphologic, Dynamic and Functional AspectsDynamics of Primate Follicular Growth: A Physiologic PerspectiveFunctional Consequences of Mutations and Polymorphisms in Gonadotropin and Gonadotropin Receptor GenesThe Regulation of Gonadotropin Receptor in the OvaryProstaglandin Biosynthesis and Action in the OvaryActions of Insulin IGF-I on sterol-metabolizing Gene Expression in Ovarian CellsIntracellular Cholesterol Dynamics in Steroidogenic CellsRegulation of Mammalian Oocyte MaturationOocyte-Granulosa Cell InteractionsOvulation: An Inflammatory Cascade of Gene ExpressionThe Function and Regulation of Cell Populations ComposingThe Corpus Luteum of the Ovarian CycleLuteinizationThe Corpus Luteum of PregnancyPotential Role of Cytokines in Ovarian Physiology: The Case for Interleukin-1Activin, Inhibin and Follistatin in Ovarian PhysiologyGnRH as an Autocrine Regulator in the Human OvaryOvarian AngiogenesisApoptosis in Ovarian Development, Function and FailureReactive Oxygen Species and Ovarian FunctionFollicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular AtresiaGeneration and Application of Ovarian Steroidogenic Cell LinesThe Application of Gene Ablation and Related Technologies to the Study of Ovarian FunctionBioinformatic Analysis of Ovarian Genes Using an Ovary-Specific DatabaseHuman Ovarian Pathophysiology: Select AspectsGonadotropin Ovulation InductionThe Role of GnRH Antagonists in Supporting Ovarian HyperstimulationThe Ovarian Factor in Assisted Reproductive TechnologyOvarian Function in Assisted ReproductionPolycystic Ovary SyndromeThe Role of the Ovary in the Genesis of HyperandrogenismLuteal DysfunctionGerm Cell Failure and Ovarian Resistance: Human Genes and DisordersOvarian Function and Survival of Patients with Cervical Carcinoma Treated with Radical Hysterectomy and Ovarian TranspositionRole of Mitochondria in the Aging OvaryDevelopment & Differentiation of Ovarian Surface Epithelium: Cues for the Basis of its Malignant PotentialMolecular Mechanisms of Ovarian Neoplastic ProgressionOvarian CarcinogenesisThe Role of X-Linked Inhibitor of Apoptosis Protein in Chemoresistant Ovarian Cancer