The Organic Chemistry of Drug Design and Drug Action
- Richard B. Silverman, Ph.D Organic Chemistry, Northwestern University, Evanston, IL, USA
- Mark W. Holladay, Ambit Biosciences, San Diego, CA, USA
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage.
Undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.