Cognitive Neuroscience and Neuropathology

Edited by

  • Steven Laureys, Coma Science Group, Cyclotron Research Center; Department of Neurology, Liège University Hospital, Belgium; Belgian National Funds for Scientific Research; Belgian Royal Academy of Sciences
  • Giulio Tononi, University of Wisconsin School of Medicine, USA

Understanding consciousness is the major unsolved problem in biology. One increasingly important method of studying consciousness is to study disorders of consciousness, e.g. brain damage and disease states leading to vegetative states, coma, minimally conscious states, etc. Many of these studies are very much in the public eye because of their relationship to controversies about coma patients (e.g. Terry Schiavo case in the US recently), and the relationship to one of the major philosophical, sociological, political, and religious questions of humankind.This is the first book to summarize our current understanding of the neuroanatomical and functional underpinnings of human consciousness by emphasizing a lesional approach offered via the study of neurological patients. The selected contributors are all outstanding authors and undisputed leaders in their field.
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Researchers and graduate students in:Cognitive NeuroscienceCognitive NeurologyNeuroscienceTranslational NeuroscienceNeurologyPsychiatryNeuropsychologyCognitive PsychologyClinical Psychology


Book information

  • Published: October 2008
  • ISBN: 978-0-12-374168-4


"This is a very welcome addition to the field of neuroscience literature and should be read by anyone involved in the care of persons with disorders of consciousness... I would highly recommend the text to any clinician involved in the neurosciences with an interest in consciousness and/or disorders of consciousness. It is well worth the asking price and is an excellent source of current information on the topic. Overall rating 9 out of 10." - Nathan Zasler, MD, Chief Editor, NeuroTrauma Letter, Chairperson, IBIA, Medical Director and CEO, Tree of Life and Concussion Care Centre of Virginia

"Laureys and the Liege school have shifted the paradigm in the clinical understanding of disturbed consciousness. He and Tononi have edited a ground breaking book. In this field the book to have and read next to Plum and Posner's Diagnosis of Stupor and Coma is now Laureys and Tononi. Clinicians need to be aware of the recent rapid advances in consciousness studies, many occasioned by imaging and non-invasive brain monitoring, because they will affect management of their most vulnerable patients." - Richard Frackowiak, University College London and Ecole Normale Supérieure, Paris

"An outstandingly unique book reassembling the most recent data of the rising science of consciousness." - Jean-Pierre Changeux, College de France

“Here, at last, is a survey of the way that damage to the brain alters consciousness. This volume is a well-equipped hardware shop with most of the pieces that are needed to build a state-of-the-art model of how the brain performs its most magical function, the creation of a self that sees, perceives, knows that it does so, and dares to ask how.” - Allan Hobson, Harvard Medical School, Boston, USA

Table of Contents

Preface: Steven Laureys and Giulio Tononi1. Consciousness: an overview of the phenomenon and of its possible neural basisAntonio Damasio and Kaspar Meyer2. The neurological examination of consciousness: Hal Blumenfeld3. Evaluating consciousness by measuring brain function: Steven Laureys, Joy Hirsch, Boris Kotchobey & Giulio Tononi4. Consciousness and neural synchronization: Wolf Singer5. Neural correlates of visual consciousness: Geraint Rees6. The relationship between consciousness and attention: Naotsugu Tsuchiya1 and Christoph KochWAKING, SLEEP AND ANESTHESIA7. Intrinsic Brain Activity and Consciousness: Marcus Raichle and Abraham Z. Snyder8. Sleep and dreaming: Giulio Tononi9. Sleepwalking: Claudio Bassetti 10. General Anesthesia and Consciousness: Michael AlkireCOMA AND RELATED CONDITIONS11. Coma: Bryan Young12. Brain death: James Bernat13. The Assessment of Conscious Awareness in the Vegetative State: Adrian Owen, Nicholas Schiff & Steven Laureys14. The Minimally Conscious State: Clinical Features, Pathophysiology and Therapeutic Implications: Joseph Giacino & Nicholas Schiff15. Locked-in syndrome: Steven Laureys16. Dementia : Pietro Pietrini, Paulo Nichelli & Eric Salmon17. Brain-computer interfaces for communication in paralysed patients and implications for disorders of consciousness: Andrea Kubler18. Neuroethics and Disorders of Consciousness: A Pragmatic Approach to Neuro-palliative Care: Joseph FinsSEIZURES, SPLITS, NEGLECTS, AND ASSORTED DISORDERS 19. Epilepsy and Consciousness: Hal Blumenfeld20. The Left Hemisphere Does Not Miss the Right Hemisphere: Michael Gazzaniga and Michael B. Miller21. Visual consciousness: an updated neurological tour: Lionel Naccache22. The neurophysiology of self-awareness disorders in conversion hysteria: Patrick Vuillemier23. Leaving body and life behind : Out-of-body and near-death experience: Olaf Blanke & Sebastian Dieguez24. The hippocampus, memory, and consciousness: Bradley R. Postle25. Syndromes of Transient Amnesia: Adam Zeman & Chris Butler26. Consciousness and aphasia : Paulo Nichelli27. Blindness and Consciousness: New Light from the Dark: Pietro Pietrini, Maurice Ptito, Ron Kupers28. The Neurology of Consciousness: An Overview: Giulio Tononi & Steven Laureys