The Molecular Basis of Cancer book cover

The Molecular Basis of Cancer

The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application.

Oncology and Hematology

Hardbound, 888 Pages

Published: February 2014

Imprint: Saunders

ISBN: 978-1-4557-4066-6


  • The Molecular Basis of Cancer, 4e

    Mendelsohn, Howley, Israel, Gray, Thompson


    Part I: Carcinogenesis and Cancer Genetics

    1. Cancer, A Genetic Disorder

    2. Oncogenes and Signal Transduction

    3. Tumor Suppressor Genes

    4. Genomic Instability and DNA Repair

    5. Epigenetics and Cancer

    6. Infectious Agents and Cancer

    7. Environmental Carcinogenesis

    8. Animal Models: Flies, Fish and Yeast

    9. Genetic Mouse Models of Cancer

    Part II: Cancer Biology

    10. Cancer Stem Cells

    11. Regulation of the Cell Cycle

    12. Cell Growth

    13. Cancer Cell Metabolism

    14. Apoptosis, Autophagy and Necrosis

    15. Cell Growth Arrest and Senescence

      16. Stromal-Cancer Interactions in the Microenvironment

      17. Hypoxia and Angiogenesis

    18. Invasion and Metastasis

    19. Inflammation and Cancer

      20. Molecular Pathways and Systems Biology

    Part III: Molecular Pathology and Diagnostics

    21. Biomarkers Assessing Risk of Cancer

    22. Biomarkers for Detecting Cancer: Molecular Screening

      23. Biomarkers for Predicting Response to Specific Therapy

    24. The Technology of Analyzing Nucleic Acids

    25. Imaging Cancer



advert image