The Lung

Development, Aging and The Environment

Edited by

  • Kent Pinkerton, University of California, Davis, USA
  • Richard Harding, Monash University, Clayton, Australia
  • Kent Pinkerton, University of California, Davis, USA
  • Richard Harding, Monash University, Clayton, Australia
  • Charles Plopper, University of California, Davis, USA

This unique book provides a concise account, written by world authorities in their fields, of how the mammalian lung grows and matures before birth and how the lungs, and their ability to function well, can be affected by the environment and by genetic factors, both before and after birth. It provides an understanding of the basis of some major lung diseases affecting infants and children. The book also deals with how the lung changes with age, and how the process of lung aging can be affected by the environment.
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Graduate and post-graduate respiratory, pulmonary, thoracic scientists and physicians; pediatricians; gerontologists; perinatologists; pharmacologists; epidemiologists and toxicological, health, environmental regulators.


Book information

  • Published: November 2003
  • ISBN: 978-0-12-324751-3

Table of Contents

PrefaceIntroductionCRITICAL EVENTS IN NORMAL DEVELOPMENT AND AGING Lung Morphogenesis, role of growth factors and transcription factorsDevelopment of Airway EpitheliumDevelopment of the Airway InnervationDevelopment of AlveoliDevelopment of the Pulmonary Basement MembraneDevelopment of the Pulmonary Vascular Developmental Physiology of the Pulmonary CirculationDevelopment of Fluid Transport Across Pulmonary EpitheliaPhysical, Endocrine and Growth Factors in Lung DevelopmentDevelopment of the Pulmonary Surfactant SystemDevelopment of the Pulmonary Immune SystemDevelopment of Antioxidant and Xenobiotic Metabolizing Enzyme Systems Compensatory Lung GrowthPulmonary Transition at BirthNormal Aging of the LungENVIRONMENTAL INFLUENCES ON LUNG DEVELOPMENT AND AGINGPulmonary Consequences of Premature BirthRole of Nutrition in Lung Development Before and After BirthInfluence of High Altitude on Lung Development and FunctionGenetic Factors Involved in Susceptibility to Lung DiseaseEffects of Environmental Tobacco Smoke on Lung DevelopmentNicotine Exposure During Early Development- effects on the lungExposure to Allergens During Development Development of Atopy in ChildrenEffects of Air Pollution on Lung Function Development and Asthma Occurence Environmental Toxicants and Lung Development in Experimental ModelsRepair of Environmental Lung Injury During DevelopmentEffects of Aging, Disease and the Environment on the Pulmonary Surfactant SystemEnvironmental Determinants of Lung Aging