The Kidney in Systemic Autoimmune Diseases

Series Editor:

  • Ronald Asherson, Killarney, Johannesburg, South Africa

Edited by

  • Justin Mason, PhD FRCP, Professor of Vascular Rheumatology, Bywaters Centre for Vascular Inflammation, Imperial College London, Hammersmith Hospital, London, UK
  • Charles Pusey, Renal Section, Division of Medicine, Imperial College London, Hammersmith Hospital, U.K.

This volume brings together an international group of clinicians and clinical scientists to contribute to a state-of the-art review of the underlying pathogenic mechanisms, methods of clinical assessment, classification and diagnosis of renal disease, combined with a detailed overview of treatment strategies. An essential reference source for all those involved with the care of patients with renal involvement in systemic autoimmune disease, and for those contributing to research into the underlying pathogenic mechanisms in these disorders.
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Internal medicine and renal physicians, rheumatologists, paediatricians, clinical immunologists and general practitioners


Book information

  • Published: December 2007
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-52972-5

Table of Contents

Pathogenic MechanismsPathogenesis of renal disease - autoimmunity Pathogenesis of renal disease - complement Pathogenesis of renal disease - cytokines & other soluble factors Pathogenesis of renal disease - cellular mechanisms Pathogenesis of renal disease - renal cell response to injury Renal toxicity of drugs used in systemic AI disease The vasculitidesAASV - mechanisms AASV - clinical features and treatment Large and medium vessel vasculitis - mechanisms Large and medium vessel vasculitis - clinical features & Rx Anti-GBM - mechanisms, clinical features and treatment Cryoglobulinaemic vasculitis HSP HUS/TTP The connective tissue diseasesSLE - mechanisms SLE - renal involvement SLE - treatment APS Sjögrens syndrome Systemic sclerosis Amyloidosis Miscellaneous (Inflammatory arthritis, sarcoid, Behcets)