The Immune Response book cover

The Immune Response

Basic and Clinical Principles


Published: November 2005

Imprint: Academic Press

ISBN: 978-0-12-088451-3


  • " comes as a gratifying surprise to find that just two people have been able to compile a comprehensive treatise, The Immune Response, on the topic...sets a high standard of excellence in the immunologic literature." - Robert S. Schwartz, M.D. for THE NEW ENGLAND JOURNAL OF MEDICINE "This is a valuable book for any veteran immunologist or student of immunology, with its ability to make difficult concepts easy to understand through clear explanations and illustrations its major attraction." - Sam Mehr, MBBS, BMedSci, The Children's Hospital at Westmead for Doody's: 3 Star Review "A major strength of this text is that two authors wrote it with the assistance of two contributors, so that the information is integrated across the chapters and the style is consistent throughout rather than each chapter being written by a different author or set of authors with the editors then trying to integrate the information afterward. excellent new textbook that combines excellent chapters on basic immunology with very good introductory chapters on clinical disorders related to immunology. This book will be particularly useful to serious students entering the field or to those in the field who want a well-written update across the breadth of immunology" - Andrew Saxon for CLINICAL IMMUNOLOGY (Jan 2006) "...transitions smoothly from chapter to chapter, without the jarring inconsistency of writing styles that sometimes plagues multiauthor texts. The original two-color illustrations, fullcolor plates, and ample sidebars and summary boxes make for a pleasing, learner-centered book. The Immune Response is a well-written, well-organized, learner-centered text that is suitable for undergraduates, medical and graduate students, and more advanced learners of immunology." - James T. Li for JAMA (March 2006) "...very erudite and quite complete and accurate in its coverage..." -Peter Ward, University of Michigan Health Systems, Department of Pathology, USA (2004) "...very timely, reads very well, and should be of great interest to those wanting to get a start in understanding Immunology..." - Juan-Carlos Zuniga-Pflucker, Sunnybrook & Women's College Heath Sciences Centre, USA (2004) "The illustrations are terrific...One of the things I especially like is the use of the "Introducing..." and "More about..." sections. These give students a taste of what is to come without overwhelming them with details." - Douglas Green, La Jolla Institute of Allergy and Immunology, USA (2004) "...straight forward style...crystal clear definitions of complex immunological concepts...Uncomplicated style effortless for the reader to move from one section to the next, comfortable, unforced learning experience..." -Gillian Wu, Faculty of Pure and Applied Science, York University, Canada "A very readable and enjoyable text.... Historical background is a nice idea that is essentially overlooked in many competing texts.....contemporary and would be easy to recommend..." -Richard M. Locksley, Department of Medicine, University of California in San Francisco, HHMI, San Francisco, CA, USA "I particularly like the clear and conversational style of the prose...chapters are a delight to read...I {also} like the format of presentation with boxes for the specialists and plenty of illustration... This will be an important contribution to the field of Immunology." -Noel R. Rose, Director, Center for Autoimmune Disease Research, the Johns Hopkins University, Baltimore, MD, USA "This book is an important contribution, providing the reader with a clear, complete, and concise overview of the immune system in both health and disease...This is a valuable book for any veteran immunologies or student of immunology, with its ability to make difficult concepts easy to understand through clear explanations and illustrations its major attraction." -Sam Mehr, MBBS, BMedSci (The Children's Hospital at Westmead)


  • BASIC IMMUNOLOGYPerspective on ImmunityIntroduction to the Immune ResponseCells and Tissues of the Immune ResponseInnate ImmunityB Cell Receptor Structure and Effector FunctionAntigen-Antibody InteractionExploiting Antigen-Antibody InteractionThe Immunoglobulin GenesThe Humoral Response: B Cell Development and ActivationThe Major Histocompatibility ComplexAntigen Processing and PresentationT Cell Receptor: Structure of its Proteins and GenesT Cell DevelopmentT Cell ActivationT cell differentiation and effector functionImmune Tolerance in the PeripheryCytokines and their ReceptorsBridging Innate and Specific Immunity: NK, gd T and NKT cellsComplementMucosal and Cutaneous ImmunityComparative ImmunologyCLINICAL IMMUNOLOGYImmunity to PathogensVaccines and Clinical Immunization Primary ImmunodeficienciesHIV and Acquired Immunodeficiency SyndromeTumor ImmunologyTransplantationAllergy and HypersensitivityAutoimmune DiseaseGlossaryAppendices IndexAbbreviations


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