The Harriet Lane Handbook of Pediatric Antimicrobial Therapy book cover

The Harriet Lane Handbook of Pediatric Antimicrobial Therapy

Mobile Medicine Series (Expert Consult: Online + Print)

From the experts at Johns Hopkins University who bring you the bestselling Harriet Lane Handbook, the Harriet Lane Handbook of Pediatric Antimicrobial Therapy delivers quick, dependable answers to help you effectively treat a broad spectrum of pediatric infectious diseases. This highly regarded medical reference book is your pocket-sized source for all of the evidence-based recommendations you need to provide the best possible care to your young patients.


Paperback, 640 Pages

Published: July 2013

Imprint: Saunders

ISBN: 978-0-323-11247-5


  • "...straighforward language and sound structure, with a wealth of information available in pocket form for the busy house officer or resident in pediatric departments all over the world. I can only give my highest recommendation."
    International Journal of Adolescent Medicine and Health, 2009



    Notes and Abbreviations Used in Tables

    1. Infectious Agents and Drugs of Choice

    I. Recommended Treatment for Bacterial Infections

    II. Recommended Treatment for Mycobacterial Infections

    III. Recommended Treatment for Viral Infections

    IV. Recommended Treatment for Fungal Infections

    V. Recommended Treatment for Parasitic and Protozoal Infections

    2. Recommended Empiric Antimicrobial Therapy for Selected Clinical Syndromes

    3. Drug Dosing in Special Circumstances

    4. Mechanisms of Action and Routes of Administration of Antimicrobial Agents

    5. Mechanisms of Drug Resistance

    I. Common Mechanisms of Microbial Resistance

    II. Discordance Between in Vitro Susceptibility and in Vivo Efficacy

    6. Therapeutic Drug Monitoring

    I. General Principles

    II. Antimicrobials Requiring Therapeutic Drug Monitoring

    III. Special Topics in Antimicrobial Therapeutic Drug Monitoring

    IV. Pharmacokinetic Monitoring in Therapeutic Drug Monitoring

    V. Pharmacokinetic/Pharmacodynamic (PK/PD) Antimicrobial Relationships

    VI. Drug Interactions

    7. Adverse Drug Reactions

    I. Blood

    II. Cardiovascular

    III. Central Nervous System

    IV. Skin

    V. Gastrointestinal

    VI. Endocrine/METABOLIC

    VII. Renal/Genitourinary

    VIII. Respiratory

    IX. Hepatic

    X. Ocular

    XI. Musculoskeletal

    XII. Hypersensitivity

    XIII. Other

    8. Recommended Antimicrobial Prophylaxis for Selected Infectious Agents and Conditions

    9. Antimicrobial Desensitization Protocols

    I. Penicillin

    II. Amoxicillin

    III. Cephalosporins

    IV. Trimethoprim/Sulfamethoxazole (TMP/SMX) Oral

    V. Fluoroquinolone

    VI. Vancomycin

    VII. Aminoglycosides

    VIII. Clindamycin

    IX. Linezolid

    X. Darunavir

    10. Formulary


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