The Flaviviruses: Detection, Diagnosis and Vaccine Development

Edited by

  • Thomas Chambers
  • Thomas Monath, 1

Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat.Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research.
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Virologists, molecular epidemologists, clinicians and public health specialists, immunologists, and researchers in vaccine development


Book information

  • Published: December 2003
  • ISBN: 978-0-12-039861-4


"...the chapters are well written, and the editors have ensured continuity of a high standard of writing throughout the set...Given the wealth of information, with contributions by over 60 authors, The Flavaviruses, really is an essential series of books that belongs on every arbovirologists’ bookshelf." -Stephen Higgs, Ph.D., University of Texas Medical Branch, U.S. (2004)

Table of Contents

Diagnosis and SurveillanceSerodiagnosis of Flaviviral Infections and Vaccinations in HumansMolecular amplification assays for the detection of FlavivirusesVirus Epidemiology, Ecology and EmergenceJapanese EncephalitisEpidemiology of St Louis encephalitis virusWest Nile Virus: epidemiology and Ecology in North AmericaDengue Epidemiology: Virus Epidemiology, Ecology and Emergence.Epidemiology and Ecology of Yellow Fever virusVirus Epidemiology, Ecology and Emergence of Tick-borne flavivirusesVaccines and Antiviral AgentsFormalin-inactivated whole virus and recombinant subunit flavivirus vaccinesEmpirically derived live, attenuated vaccines against Dengue and Japanese EncephalitisDNA vaccines for FlavivirusesChimeric Flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis and Japanese encephalitis Prospects for antiviral therapy