The Cerebellum: From Structure to Control

Edited By

  • C.I. De Zeeuw, Department of Anatomy, Erasmus University Rotterdam, Dr. Molewaterplein 50, Rotterdam, The Netherlands
  • P. Strata, Human Anatomy and Physiology, University of Turin, Corso Raffaelo 30, Torino, Italy.
  • J. Voogd, Department of Anatomy, Erasmus University Rotterdam, Dr. Molewaterplein 50, Rotterdam, The Netherlands

Many of the cerebellar scientists of the established generation have contributed substantially to the quality of this issue. In addition, the book is marked by chapters from the coming generations of scientists who will determine the direction of cerebellar research for the next century. As in other fields of neuroscience, this research will be dominated by molecular neurobiology and new functional imaging techniques. Altogether, the book is pluriform and unique in that it is multidisciplinary, in that it promotes different views on cerebellar function, and that it is being published on the verge of different era's dominated by different generations of cerebellar scientists. The wealth of new information and ideas contained in these important papers will stimulate even more intensive research in the twenty-first century leading to a greater understanding of cerebellar function(s).
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Book information

  • Published: May 1997
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-82313-7

Table of Contents

List of contributors. Preface. Acknowledgements. I. Development and compartmentation of cerebellar cortex.1. Functional cloning of candidate genes that regulate purkinjecell-specific gene expression. 2. Transverse and longitudinalpatterns in the mammalian cerebellum. 3. An anatomical model ofcerebellar modules. II. Neurotransmission in cerebellarcortex. 4. The distribution of corticotropin-releasing factor(CRF), CRF binding sites and CRF1 receptor mRNA in themouse cerebellum. 5. The physiological effects of serotonin onspontaneous and amino acid-induced activation of cerebellarnuclear cells: an in vivo study in the cat. 6. Cholinergicinnervation and receptors in the cerebellum. 7. Molecularorganization of cerebellar glutamate synapses. 8.Compartmentalised distribution of GABAA and glutamatereceptors in relation to transmitter release sites on the surfaceof cerebellar neurons. III. Unipolar brush cells in cerebellarcortex. 9. The unipolar brush cells of the mammaliancerebellum and cochlear nucleus: cytology and microcircuitry. 10.Physiology of transmission at a giant glutamatergic synapse incerebellum. IV. Anatomy and physiology of cerebellarnuclei. 11. Cerebellar nuclei: the olivary connection. 12.Functional significance of excitatory projections from theprecerebellar nuclei to interpositus and dentate nucleus neuronsfor mediating motor, premotor and parietal cortical inputs. 13.Involvement of cerebellar cortex and nuclei in the genesis andcontrol of unconditioned and conditioned eyelid motor responses.V. Pontocerebellar connections. 14. Salient anatomicfeatures of the cortico-ponto-cerebellar pathway. 15. Mossy-fibresensory input to the cerebellum. VI. Plasticity inolivocerebellar system. 16. Reciprocal trophic interactionsbetween climbing fibres and purkinje cells in the rat cerebellum.17. Intrinsic properties and environmental factors in theregeneration of adult cerebellar axons. VII. Vestibulocerebellar coordination of movements.18. Signal processing in the C2 module of the flocculus and itsrole in head movement control. 19. Control of thethree-dimensional dynamic characteristics of the angularvestibulo-ocular reflex by the nodulus and uvula. 20. Cholinergiccontrol in the floccular cerebellum of the rabbit. 21.Behavioural analysis of purkinje cell output from the horizontalzone of the cat flocculus. VIII. Vestibulocerebellarlearning. 22. Characterization of purkinje cells in thegoldfish cerebellum during eye movement and adaptive modificationof the vestibulo-ocular reflex. 23. Role of the y-group of thevestibular nuclei and flocculus of the cerebellum in motorlearning of the vertical vestibulo-ocular reflex. IX.Cerebellar coordination of movements. 24. Aspects ofcerebellar function in relation to locomotor movements. 25. Thecontrol of forelimb movements by intermediate cerebellum. 26.What features of visually guided arm movements are encoded in thesimple spike discharge of cerebellar Purkinje cells. 27. Someorganizing principles for the control of movement based onolivocerebellar physiology. 28. Is the cerebellum sensory formotors sake, or motor for sensorys sake: the view from thewhiskers of a rat? X. Cerebellar learning and cognition.29. Cerebellar contributions to the acquisition and execution oflearned reflex and volitional movements. 30. A new functionalrole for cerebellar long term depression. 31. On the role of thecerebellum and basal ganglia in cognitive signal processing. 32.Dentate output channels: motor and cognitive components. XI.Cerebellar diseases. 33. The genetic basis of hereditaryataxia. 34. Buspiron a serotonergic 5-HT1A agonist, isactive in cerebellar ataxia. A new fact in favor of theserotonergic theory of ataxia. 35. Cerebellar somatotopicrepresentation and cerebro-cerebellar interconnections. Subjectindex.