The Central Neural Organization of Cardiovascular ControlEdited by
- J. Ciriello
- M.M. Caverson
- C. Polosa
The Satellite Symposium of the 18th Annual Meeting of the Society for Neuroscience, "Function of the Ventrolateral Medulla in the Control of the Circulation", held in Ontario, Canada, focussed on the newest research developments into the central neural organisation of cardiovascular control. The central nervous system is vital in the controlling of arterial pressure via the regulation of sympathetic and parasympathetic nervous discharge to blood vessels and the heart. The central nervous system also controls the release of hormones that regulate the circulation and couple the circulatory system to different behaviours. This volume concentrates on the most recent experimental advances in the neurosciences. Current research disproves the concept of a vasomotor medullary centre, suggesting instead that the control of sympathetic preganglionic activity occurs via neural pathways. The pathways of greatest significance are proposed to originate from neurons located on, or close to, the ventral surface of the medulla oblongata. The proceedings of this symposium represent an important breakthrough in neuroscientific research. An indispensable resource book.
Progress in Brain Research
Published: December 1989
- List of Chairmen and Speakers. Preface. Introduction - Thirty years of research on ventral medulla: the way from Hans Loeschcke's first discovery to modern concepts of ventral medullary function in cardiorespiratory control (H.P. Koepchen). SECTION I: CENTRAL PROJECTIONS AND NEUROCHEMISTRY OF VENTROLATERAL MEDULLARY NEURONS. 1. Relation of enkephalin-like immunoreactive neurons to other neuropeptide and monoamine containing neurons in the ventrolateral medulla (J. Ciriello and M.M. Caverson). 2. Chemical neuroanatomy of the parapyramidal region of the ventral medulla in the rat (C.J. Helke, K.B. Thor and C.A. Sasek). 3. Adrenergic neurons in the rostral ventrolateral medulla: ultrastructure and synaptic relations with other transmitter identified neurons (T.A. Milner et al.). 4. Central control of the circulation by the rostral ventrolateral reticular nucleus: anatomical substrates (D.A. Ruggiero et al.). SECTION II: CONTRIBUTION OF VENTROLATERAL MEDULLARY NEURONS TO VASOMOTOR TONE. 5. Inhibitory vasomotor neurons in the caudal ventrolateral region of the medulla oblongata (W.W. Blessing and Y.-W. Li). 6. Differential regulation of sympathetic nerve activity by lateral and medial subregions of the rostral ventral medulla (K.J. Varner et al.). 7. Sympathoexcitatory neurons of the rostroventrolateral medulla and the origin of the sympathetic vasomotor tone (P.G. Guyenet, J.R. Haseeton and M.-K. Sun). 8. Basis for the naturally occurring activity of rostral ventrolateral medullary sympathoexcitatory neurons (S.M. Barman and G.L. Gebber). 9. A physiologically-based model of the brain stem generator of sympathetic nerve discharge (G.L. Gebber and S.M. Barman). SECTION III: EFFECT OF VENTROLATERAL MEDULLARY INPUTS ON SYMPATHETIC PREGANGLIONIC NEURON ACTIVITY. 10. Some properties of the sympathoinhibition from the caudal ventrolateral medulla oblongata in the cat (K. Dembowsky, J. Czachurski and H. Seller). 11. A glutamate mechanism in the intermediolateral nucleus mediates sympathoexcitatory responses to stimulation of the rostral ventrolateral medulla (S.F. Morrison et al.). 12. Cholinergic mechanisms subserving cardiovascular function in the medulla and the spinal cord (H.N. Sapru). 13. Multiple actions of noradrenaline on sympathetic preganglionic neurons of the cat studied in the spinal cord slice (M. Yoshimura, C. Polosa and S. Nishi). SECTION IV: Cardiovascular and respiratory integration by ventrolateral medullary neurons. 14. Specific areas of the ventral medulla controlling sympathetic and respiratory activities and their functional synchronization in the rat ( S. Baradziej and A. Trzebski). 15. Role of the ventrolateral medulla in the cardiovascular responses to changes in the carbon dioxide tension in the arterial blood (F. Lioy). 16. Integration of cardiorespiratory responses in the ventrolateral medulla (N.S. Cherniack et al.). SECTION V: NEURONAL CIRCUITRY IN THE VENTROLATERAL MEDULLA INVOLVED IN INTEGRATIVE FUNCTION. 17. Integrated function of neurons in the rostral ventrolateral medulla (T.A. Lovick and P. Li). 18. The selectivity of descending vasomotor control by subretrofacial neurons (R.M. McAllen and R.A.L. Dampney). 19. Role of the glycine sensitive area in the regulation of cardiac output (R.R. Campos Jr. and P.G. Guertzenstein). 20. Pressor responses to muscular contraction in the cat: contributions by caudal and rostral ventrolateral medulla (G.A. Iwamoto et al.). 21. Cardiovascular control by the rostral ventrolateral medulla in the conscious dog (K.J. Dormer and T.G. Bedford). SECTION VI: CONTROL OF NEUROHYPOPHYSICAL HORMONE RELEASE BY VENTROLATERAL MEDULLARY NEURONS. 22. Organization of ventrolateral medullary afferents to the hypothalamus (M.M. Caverson and J. Ciriello). 23. Involvement of caudal ventrolateral medulla neurons in mediating visceroreceptive information to the hypothalamic paraventricular nucleus (H. Yamashita, H. Kannan and Y. Ueta). 24. Control for neurosecretory vasopressin cells by noradrenergic projections of the caudal ventrolateral medulla (T.A. Day). 25. Nucleus tractus solitarius innervation of supraoptic nucleus: anatomical and electrophysiological studies in the rat suggest differential innervation of oxytocin and vasopressin neurons (W.N. Raby and L.P. Renaud). Conclusions. Subject Index.