The Brain as a Drug Target

Edited by

  • Shafiqur Rahman, Professor, Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD, USA

The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.
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Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.


Book information

  • Published: January 2011
  • ISBN: 978-0-12-385506-0


"Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal

Table of Contents

  1. Monoamine Transporters: Vulnerable and Vital Doorkeepers
  2. Zhicheng Lin, Juan J. Canales, Thröstur Björgvinsson, Morgane M. Thomsen, Hong Qu, Qing-Rong Liu, Gonzalo E. Torres, and S. Barak Caine

  3. Therapeutic Targets in Alzheimer Disease and Related Tauopathies
  4. Christopher P. Corbo and Alejandra del C. Alonso

  5. Therapeutic Targets for Neuroprotection and/or Enhancement of Functional Recovery Following Traumatic Brain Injury
  6. Matthew L. Kelso and James R. Pauly

  7. Insulin, Synaptic Function, and Opportunities for Neuroprotection
  8. John G. Mielke and Yu-Tian Wang


  9. Molecular Alterations in Glioblastoma: Potential Targets for Immunotherapy
  10. Azizul Haque, Naren L. Banik, and Swapan K. Ray

  11. Molecular Signaling and Translational Significance of the Corticotropin Releasing Factor System
  12. Patrick J. Ronan, and Cliff H. Summers

  13. Molecular targets of alcohol action: translational research for pharmacotherapy development and screening
  14. Giorgio Gorini, Richard L. Bell, and R. Dayne Mayfield

  15. Brain Nicotinic Receptors as Emerging Targets for Drug Addiction: Neurobiology to Translational Research
  16. Shafiqur Rahman

  17. Glutamatergic Neuroplasticity in Cocaine Addiction
  18. Joachim D. Uys and Kathryn J. Reissner

  19. Role of the serotonergic system in alcohol dependence: from animal models to clinics

Verity R. Johnson, Jason M. Weedman, Youssef Sari