The Brain as a Drug Target book cover

The Brain as a Drug Target

The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Hardbound, 468 Pages

Published: January 2011

Imprint: Academic Press

ISBN: 978-0-12-385506-0


    "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal


    1. Monoamine Transporters: Vulnerable and Vital Doorkeepers
    2. Zhicheng Lin, Juan J. Canales, Thröstur Björgvinsson, Morgane M. Thomsen, Hong Qu, Qing-Rong Liu, Gonzalo E. Torres, and S. Barak Caine

    3. Therapeutic Targets in Alzheimer Disease and Related Tauopathies
    4. Christopher P. Corbo and Alejandra del C. Alonso

    5. Therapeutic Targets for Neuroprotection and/or Enhancement of Functional Recovery Following Traumatic Brain Injury
    6. Matthew L. Kelso and James R. Pauly

    7. Insulin, Synaptic Function, and Opportunities for Neuroprotection
    8. John G. Mielke and Yu-Tian Wang


    9. Molecular Alterations in Glioblastoma: Potential Targets for Immunotherapy
    10. Azizul Haque, Naren L. Banik, and Swapan K. Ray

    11. Molecular Signaling and Translational Significance of the Corticotropin Releasing Factor System
    12. Patrick J. Ronan, and Cliff H. Summers

    13. Molecular targets of alcohol action: translational research for pharmacotherapy development and screening
    14. Giorgio Gorini, Richard L. Bell, and R. Dayne Mayfield

    15. Brain Nicotinic Receptors as Emerging Targets for Drug Addiction: Neurobiology to Translational Research
    16. Shafiqur Rahman

    17. Glutamatergic Neuroplasticity in Cocaine Addiction
    18. Joachim D. Uys and Kathryn J. Reissner

    19. Role of the serotonergic system in alcohol dependence: from animal models to clinics

    Verity R. Johnson, Jason M. Weedman, Youssef Sari


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