The Boundaries of Consciousness: Neurobiology and Neuropathology, 150

Edited By

  • Steven Laureys, Cyclotron Research Center and Department of Neurology, University of Liege, Belgium

Consciousness is one of the most significant scientific problems today. Renewed interest in the nature of consciousness - a phenomenon long considered not to be scientifically explorable, as well as increasingly widespread availability of multimodal functional brain imaging techniques (EEG, ERP, MEG, fMRI and PET), now offer the possibility of detailed, integrated exploration of the neural, behavioral, and computational correlates of consciousness. The present volume aims to confront the latest theoretical insights in the scientific study of human consciousness with the most recent behavioral, neuroimaging, electrophysiological, pharmacological and neuropathological data on brain function in altered states of consciousness such as: brain death, coma, vegetative state, minimally conscious state, locked-in syndrome, dementia, epilepsy, schizophrenia, hysteria, general anesthesia, sleep, hypnosis, and hallucinations. The interest of this is threefold. First, patients with altered states of consciousness continue to represent a major clinical problem in terms of clinical assessment of consciousness and daily management. Second, the exploration of brain function in altered states of consciousness represents a unique lesional approach to the scientific study of consciousness and adds to the worldwide effort to identify the "neural correlate of consciousness". Third, new scientific insights in this field have major ethical and social implications regarding our care for these patients.
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Neurologists, neuroscientists, psychologists, pharmacologists, and physiologists.


Book information

  • Published: September 2005
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-51851-4

Table of Contents

What in the world is consciousness?A neuroscientific approach to consciousnessFunctional neuroimaging during altered states of consciousness: How and what do we measureGlobal workspace theory of consciousness: Toward a cognitive neuroscience of human experience?Skill, corporality and alerting capacity in an account of sensory consciousnessMethods for studying unconscious learningComputational correlates of consciousnessMachine consciousnessConsciousness, information integration and the brainDynamics of thalamo-cortical network oscillations and human perceptionFrom synchronous neuronal discharges to subjective awareness?Genes and experience shape brain networks of conscious controlVisual phenomenal consciousness: A neurological guided tourThe mental selfPosterior cingulate, precuneal and retroplenial cortices: Cytology and components of the neural network correlates of consciousnessHuman cognition during REM sleep and the activity profile within frontal and parietal cortices. A reappraisal of functional neuroimaging dataGeneral anesthesia and the neural correlates of consciousnessBrain imaging in research on anesthetic mechanisms: Studies with propofolThe cognitive modulation of pain: Hypnosis and placebo-induced analgesiaConsciousness and epilepsy: Why are patients with absence seizures absent?Two aspects of impaired consciousness in Alzhemier's diseaseFunctional brain imaging of symptoms and cognition in schizophreniaHysterical conversion and brain functionThe out-of-body experience: Precipitation factors and neural correlatesNear-death experiences in cardiac arrest survivorsThe concept and practice of brain deathThe minimally conscious state: Defining the borders of consciousnessBehavioral evaluation of consciousness in severe brain damageEvoked potentials in severe brain injuryEvent-related potential measures of consciousness: Two equations with three unknownsNovel aspects of the neuropathology of the vegetative state after blunt head injuryUsing a hierarchical approach to investigate residual auditory cognition in persistent vegetative stateModeling the minimally conscious state: Measurements of brain function and therapeutic possibilitiesThe locked-in syndrome: What is it like to be conscious but paralysed and voiceless?Brain-computer interfaces - the key for the conscious brain locked into a paralysed bodyNeural plasticity and recovery of function30 Years of the vegetative state: Clinical, ethical and legal problemsAssessing health-related quality of life after severe brain damage: Potentials and limitationsOutcome and ethics in severe brain damageClinical pragmatism and the care of brain damaged patients: Towards a palliative neuroethics for disorders of consciousness