This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R. H. F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, and various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. This, the 58th volume in the series presents two quite different aspects of alkaloids. The first of the two chapters reviews the substantial progress made on the biotransformations of various classes of alkaloids and examines the enzymes systems involved in this process. Such studies are proving very important in the consideration of how alkaloids can be used in the future as medicinal or biological agents. The second chapter presents a comprehensive review of the known polyamine alkaloids based on their biogenesis and additionally provides overviews of their detailed structural analysis, their synthesis, biosynthesis and biology.
For chemists, pharmacologists, and biochemists