Systems Biology book cover

Systems Biology

Philosophical Foundations

Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies.

Computational biologists, Molecular biologists, Cellular biologists, Systems biologists, Bioinformaticians, Philosophers of Science, Philosophers of Biology

Hardbound, 360 Pages

Published: March 2007

Imprint: Elsevier

ISBN: 978-0-444-52085-2


  • Introduction1. Towards philosophical foundations of Systems Biology: IntroductionResearch programs of Systems Biology 2. The methodologies of Systems Biology3. Methodology is Philosophy4. How can we understand metabolism?5. On Building Reliable Pictures with Unreliable Data: an Evolutionary and Developmental Coda for the New Systems Biology?Theory / models 6. Mechanism and mechanical explanation in cell biology7. Theories, Models, and Equations in Systems Biology8. All models are wrong.......some more than others9. Data without models merging with models without dataOrganization in biological systems10. The biochemical factory that autonomously fabricates itself: a systems-biological view of the living cell11. A systemic approach to the origin of biological organization12. Organization and biological mechanisms: organized to maintain autonomy13. The disappearance of function from 'self-organizing systems'Conclusion14. Afterthoughts as foundations for Systems Biology


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