Synthesis of Essential Drugs book cover

Synthesis of Essential Drugs

This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis.
The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists.
Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis.
Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHO’s "Essential List of Drugs."
For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.
This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs.

Audience
Chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students

Hardbound, 634 Pages

Published: March 2006

Imprint: Elsevier

ISBN: 978-0-444-52166-8

Reviews

  • * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references

Contents

  • 1. General Anesthetics
    2. Local Anesthetics
    3. Analgesics
    4. Hypnotics and Sedatives
    5. Anxiolitics (Tranquilizers)
    6. Antipsycotics (Neuroleptics)
    7. Antidepressants
    8. Central Nervous System Stimulants
    9. Antiepileptics
    10. Anti-Parkinson Drugs
    11. Adrenegic (Sympatomimetic) Drugs
    12. Adrenoblocking Drugs
    13. Cholinomimetics
    14. Anticholinergic Drugs
    15. Muscle Relaxants
    16. Antihistamine Drugs
    17. Cardiac Glycosides and Other Inotropes
    18. Drugs for Tachyarrhytmias
    19. Antianginal Drugs
    20. Agents Used in Hyperlipoproteinemia
    21. Diuretics
    22. Antihypertensive Drugs
    23. Drugs for Treating of Pulmonary Diseases
    24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics
    25. Thyroid and Parathyroid Drugs
    26. Insulin and Synthetic Hypoglycemic Agents
    27. Corticosteroids
    28. Female Sex Hormones
    29. Male Sex Hormones and Anabolics
    30. Antineoplastic Agents
    31. Immunopharmacologic Drugs
    32. Antibiotics
    33. Antimicrobials
    34. Antimicobacterials
    35. Antifungal Drugs
    36. Antiviral Drugs
    37. Antiprotozoal Drugs
    38. Antihelmint Drugs

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