Synthesis of Essential DrugsBy
- Ruben Vardanyan, University of Arizona, Tucson, Arizona, USA
- Victor Hruby, University of Arizona, Tucson, Arizona, USA
This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis.
The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists.
Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis.
Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHOs "Essential List of Drugs."
For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms.
This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs.
Chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students
Hardbound, 634 Pages
Published: March 2006
- 1. General Anesthetics
2. Local Anesthetics
4. Hypnotics and Sedatives
5. Anxiolitics (Tranquilizers)
6. Antipsycotics (Neuroleptics)
8. Central Nervous System Stimulants
10. Anti-Parkinson Drugs
11. Adrenegic (Sympatomimetic) Drugs
12. Adrenoblocking Drugs
14. Anticholinergic Drugs
15. Muscle Relaxants
16. Antihistamine Drugs
17. Cardiac Glycosides and Other Inotropes
18. Drugs for Tachyarrhytmias
19. Antianginal Drugs
20. Agents Used in Hyperlipoproteinemia
22. Antihypertensive Drugs
23. Drugs for Treating of Pulmonary Diseases
24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics
25. Thyroid and Parathyroid Drugs
26. Insulin and Synthetic Hypoglycemic Agents
28. Female Sex Hormones
29. Male Sex Hormones and Anabolics
30. Antineoplastic Agents
31. Immunopharmacologic Drugs
35. Antifungal Drugs
36. Antiviral Drugs
37. Antiprotozoal Drugs
38. Antihelmint Drugs