Swaiman's Pediatric Neurology

Principles and Practice, 2-Volume Set

Swaiman’s Pediatric Neurology, by Drs. Kenneth Swaiman, Stephen Ashwal, Donna Ferriero, and Nina Schor, is a trusted resource in clinical pediatric neurology with comprehensive, authoritative, and clearly-written guidance. Extensively updated to reflect advancements in the field, this fifth edition covers new imaging modalities such as pediatric neuroimaging, spinal fluid examination, neurophysiology, as well as the treatment and management of epilepsy, ADHD, infections of the nervous system, and more. The fully searchable text is now available online at www.expertconsult.com, along with downloadable images and procedural videos demonstrating intraventricular hemorrhage and white matter injury, making this an indispensable multimedia resource in pediatric neurology.


Neurology, Pediatric Neurology

Hardbound, 2143 Pages

Published: December 2011

Imprint: Saunders

ISBN: 978-1-4377-0435-8


  • "Owning this book is a potential major hazard to workplace productivity...there is the amazing online electronic version that can lead you seamlessly from one compelling section to another, with amusing diversions via Pub Med on the way. Whole days could be passed like this, so enormously interesting, wide-ranging and well-presented is the content...This book is suitable for paediatric neurologists of all vintages and would make an excellent addition to any personal, departmental or hospital library. It is comprehensive, stimulating and engaging and I plan to direct trainees to it as a reference source. It is a long time since I put my hand in my pocket to purchase a textbook, but if I had not been fortunate enough to have been asked to review this book, I believe I would have made an exception...Swaiman et al has found a firm place on my occupational bookshelf."

    European Journal of Paediatric Neurology, November 2012,


  • Part I is Online Only Clinical Evaluation

    1 General Aspects of the Patient’s Neurologic History e1

    Kenneth F. Swaiman

    2 Neurologic Examination of the Older Child e15

    Kenneth F. Swaiman

    3 Neurologic Examination after the Newborn Period until 2 Years of Age e33

    Kenneth F. Swaiman and Lawrence W. Brown

    4 Neurologic Examination of the Term and Preterm Infant e43

    Kenneth F. Swaiman

    5 Muscular Tone and Gait Disturbances e60

    Kenneth F. Swaiman and Lawrence W. Brown

    6 Vision Loss e71

    Douglas R. Fredrick

    7 Hearing Impairment e89

    Isabelle Rapin and Oranee Sanmaneechai

    8 Vertigo e118

    Joseph M. Furman and Margaretha L. Casselbrant

    9 Taste and Smell e126

    Julie A. Mennella

    Part II is Online Only Neurodiagnostic Testing

    10 Spinal Fluid Examination e140

    David J. Michelson

    11 Pediatric Neuroimaging e151

    Nathaniel D. Wycliffe, Barbara A. Holshouser, and Stephen Ashwal

    12 Pediatric Neurophysiologic Evaluation e185

    Mark S. Scher

    Part III Emerging Neuroscience Concepts

    13 Brain Plasticity and its Disorders 3

    Michael V. Johnston

    14 Neurodegeneration in the Neonatal Brain 13

    Frances J. Northington and Lee J. Martin

    15 Neuroinflammation 29

    Pierre Gressens and Zinaida S. Vexler

    Part IV Perinatal Acquired and Congenital Neurologic Disorders

    16 Neonatal Seizures 33

    Frances E. Jensen and Faye S. Silverstein

    17 Hypoxic-Ischemic Brain Injury in the Term Newborn 47

    Steven P. Miller and Donna M. Ferriero

    18 Neonatal Brain Injury 59

    Adam Kirton, Linda S. de Vries, Lori Jordan, and Jerome Y. Yager

    19 Injury to the Developing Preterm Brain: Intraventricular Hemorrhage and White Matter Injury 77

    Laura R. Ment and Janet S. Soul

    20 Perinatal Metabolic Encephalopathies 100

    Rebecca N. Ichord

    Part V Congenital Structural Defects

    21 Overview of Disorders of Brain Development 120

    William B. Dobyns, Renzo Guerrini and A. James Barkovich

    22 Disorders of Neural Tube Development 125

    Nalin Gupta and M. Elizabeth Ross

    23 Disorders of Forebrain Development 145

    Elliott H. Sherr and Jin S. Hahn

    24 Disorders of Cerebellar and Brainstem Development 160

    Kathleen J. Millen and Joseph G. Gleeson

    25 Disorders of Brain Size 173

    Ghayda Mirzaa, Stephen Ashwal, and William B. Dobyns

    26 Malformations of Cortical Development 202

    William B. Dobyns, Renzo Guerrini, and Richard J. Leventer

    27 Hydrocephalus and Arachnoid Cysts 232

    James M. Drake and Amal Abou-Hamden

    28 Congenital Anomalies of the Skull 247

    Pedro A. Sanchez-Lara and John M. Graham, Jr.

    29 Prenatal Diagnosis of Structural Brain Anomalies 263

    Tally Lerman-Sagie, Gustavo Malinger, and Liat Ben-Sira

    Part VI Genetic, Metabolic, and Neurocutaneous Disorders

    30 Introduction to Genetics 277

    William B. Dobyns, Susan L. Christian and Soma Das

    31 Chromosomes and Chromosomal Abnormalities 307

    Maria Descartes, Bruce R. Korf and Fady M. Mikhail

    32 Aminoacidemias and Organic Acidemias 328

    Gregory M. Enns, Tina M. Cowan, Ophir Klein, and Seymour Packman

    33 Inborn Errors of Urea Synthesis 357

    Uta Lichter-Konecki and Mark L. Batshaw

    34 Diseases Associated with Primary

    Abnormalities in Carbohydrate Metabolism 368

    Marc C. Patterson and Kenneth F. Swaiman

    35 Disorders of Glycosylation 390

    Hudson H. Freeze and Marc C. Patterson

    36 Lysosomal Storage Diseases 403

    Gregory M. Pastores

    37 Mitochondrial Diseases 452

    Darryl C. De Vivo and Salvatore DiMauro

    38 Peroxisomal Disorders 468

    Gerald V. Raymond, Kristin W. Baranano, and S. Ali Fatemi

    39 Neurotransmitter-Related Disorders 486

    Matthew T. Sweney and Kathryn J. Swoboda

    40 Phakomatoses and Allied Conditions 497

    Elizabeth A. Thiele and Bruce R. Korf

    41 Degenerative Disorders Primarily of Gray Matter 518

    Rose-Mary N. Boustany and Mohamad K. El-Bitar

    42 Channelopathies 544

    Kelly Knupp, Julie A. Parsons, and Amy R. Brooks-Kayal

    Part VII Neurodevelopmental Disorders

    43 Global Developmental Delay and Mental Retardation/Intellectual Disability 554

    Elliott H. Sherr and Michael I. Shevell

    44 Cognitive and Motor Regression 575

    David J. Michelson and Stanford K. Shu

    45 Developmental Language Disorders 604

    Ruth Nass and Doris A. Trauner

    46 Dyslexia 613

    Sally E. Shaywitz and Bennett A. Shaywitz

    47 Attention-Deficit Hyperactivity Disorder 622

    David E. Mandelbaum

    48 Autistic Spectrum Disorders 638

    Deborah G. Hirtz, Ann Wagner and Pauline A. Filipek

    49 Neuropsychopharmacology 664

    Rebecca Rendleman and John T. Walkup

    Part VIII


    50 Pediatric Epilepsy: An Overview 703

    Peter R. Camfield and Carol S. Camfield

    51 Neurophysiology of Seizures and Epilepsy 711

    Carl E. Stafstrom and Jong M. Rho

    52 Genetics of Epilepsy 727

    Maria Roberta Cilio and Susannah Cornes

    53 Generalized Seizures 736

    Gregory L. Holmes

    54 Focal and Multifocal Seizures 751

    Douglas R. Nordli, Jr.

    55 Epilepsy and Neurodevelopmental

    Disorders 767

    Roberto Tuchman

    56 Myoclonic Seizures and Infantile Spasms 774

    Kendall Nash and Joseph Sullivan

    57 Febrile Seizures 790

    Shlomo Shinnar

    58 Status Epilepticus 798

    Lawrence D. Morton and John M. Pellock

    59 Antiepileptic Drug Therapy in Children 811

    Jeannine M. Conway, Ilo E. Leppik, and

    Angela K. Birnbaum

    60 The Ketogenic Diet 836

    James W. Wheless

    61 Epilepsy Surgery in the Pediatric

    Population 854

    Mary L. Zupanc and Charles J. Marcuccilli

    62 Behavioral, Cognitive, and Social Aspects

    of Childhood Epilepsy 871

    Wendy G. Mitchell, Miche`le Van Hirtum-Das, Jay Desai,

    and Quyen N. Luc

    Part IX

    Nonepileptiform Paroxysmal Disorders

    and Disorders of Sleep

    63 Headaches in Infants and Children 880

    Donald W. Lewis

    64 Breath-Holding Spells and Reflex Anoxic

    Seizures 900

    Sarah M. Roddy

    65 Syncope and Paroxysmal Disorders Other than

    Epilepsy 905

    Neil R. Friedman, Debabrata Ghosh, and Manikum


    66 Sleep-Wake Disorders 926

    Suresh Kotagal

    Part X

    Disorders of Balance and Movement

    67 The Cerebellum and the Hereditary Ataxias 939

    Paymaan Jafar-Nejad, Stephen M. Maricich, and

    Huda Y. Zoghbi

    68 Movement Disorders 965

    Terence D. Sanger and Jonathan W. Mink

    69 Cerebral Palsy 999

    Kenneth F. Swaiman and Yvonne W. Wu

    70 Tics and Tourette’s Syndrome 1009

    Harvey S. Singer

    Part XI

    White Matter Disorders

    71 Genetic and Metabolic Disorders of the White

    Matter 1020

    Adeline Vanderver and Nicole I. Wolf

    72 Acquired Disorders affecting the White

    Matter 1052

    Naila Makhani and Brenda Banwell

    Part XII

    Brain Injury and Disorders of Consciousness

    73 Impairment of Consciousness and Coma 1062

    Donald A. Taylor and Stephen Ashwal

    74 Traumatic Brain Injury in Children 1087

    Jason T. Lerner and Christopher C. Giza

    75 Non-accidental Head Trauma 1126

    Elizabeth E. Gilles and Ann-Christine Duhaime

    76 Hypoxic-Ischemic Encephalopathy in Infants

    and Older Children 1149

    Ronald M. Perkin and Stephen Ashwal

    77 Disorders of Intracranial Pressure 1185

    Mark S. Wainwright

    78 Spinal Cord Injury 1198

    N. Paul Rosman and Chellamani Harini

    79 Determination of Brain Death in Infants

    and Children 1221

    Stephen Ashwal

    Part XIII

    Infections of the Nervous System

    80 Bacterial Infections of the Nervous

    System 1241

    Martin G. Ta¨uber and Urs B. Schaad

    81 Viral Infections of the Nervous System 1262

    James F. Bale, Jr.

    82 Fungal, Rickettsial, and Parasitic Diseases

    of the Nervous System 1291

    Carol A. Glaser, Paul F. Lewis, and Janice K. Louie

    Part XIV

    Tumors and Vascular Disorders of the Nervous


    83 Tumors of the Brain and Spine 1339

    Roger J. Packer, Tobey J. MacDonald, and Gilbert Vezina

    84 Paraneoplastic Syndromes Affecting the

    Nervous System 1388

    Mustafa Khasraw and Yasmin Khakoo

    85 Cerebrovascular Disease in Children 1395

    Adam Kirton and Gabrielle deVeber

    86 Neurologic Manifestations of Rheumatic

    Disorders of Childhood 1437

    Nina Felice Schor, Emily von Scheven,

    and Stephen Ashwal

    Part XV

    Neuromuscular Disorders

    87 Normal Muscle 1463

    V. Venkataraman Vedanarayanan and Owen B. Evans, Jr.

    88 Anterior Horn Cell and Cranial Motor Neuron

    Disease 1482

    Ching H. Wang and Anne M. Connolly

    89 Peripheral Neuropathies 1503

    Stephen A. Smith and Robert Ouvrier

    90 Inflammatory Neuropathies 1532

    John T. Sladky and Stephen Ashwal

    91 Diseases of the Neuromuscular Junction 1549

    Srikanth Muppidi, Gil I. Wolfe, and Richard J. Barohn

    92 Muscular Dystrophies 1570

    Diana M. Escolar and Robert T. Leshner

    93 Congenital Myopathies 1607

    Jonathan B. Strober

    94 Metabolic Myopathies 1613

    Ingrid Tein

    95 Inflammatory Myopathies 1658

    Anthony A. Amato and John T. Kissel

    96 Channelopathies: Myotonic Disorders

    and Periodic Paralysis 1667

    Richard T. Moxley III and Chad Heatwole

    Part XVI

    Systemic and Autonomic Nervous System Diseases

    97 Endocrine Disorders of the Hypothalamus

    and Pituitary in Childhood and

    Adolescence 1690

    Qing Dong and Stephen M. Rosenthal

    98 Disorders of the Autonomic Nervous System:

    Autonomic Dysfunction in Pediatric

    Practice 1703

    Felicia B. Axelrod

    99 Disorders of Micturition and Defecation 1720

    Jennifer A. Zimmer and Bhuwan P. Garg

    100 Poisoning and Drug-Induced Neurologic

    Diseases 1731

    Laurence E. Walsh and Bhuwan P. Garg

    101 Neurologic Disorders in Children with Heart

    Disease 1758

    Catherine Limperopoulos and Adre´ J. du Plessis

    102 Interrelationships between Renal

    and Neurologic Diseases and

    Therapies 1782

    Robert S. Rust

    103 Neurologic Disorders Associated with

    Gastrointestinal Diseases and Nutritional

    Deficiencies 1821

    Yitzchak Frank and Stephen Ashwal

    104 Neurologic Complications of

    Immunization 1867

    Claudia A. Chiriboga

    Part XVII is Online Only

    Care of the Child with Neurologic Disorders

    105 Pediatric Neurorehabilitation

    Medicine e234

    Michael J. Noetzel

    106 Pain Management and Palliative

    Care e250

    John Colin Partridge

    107 Ethical Issues in Child Neurology e264

    David L. Coulter

    108 The Impact of Computer Resources on Child

    Neurology e275

    Michael M. Segal and Steven Leber

    Index i1


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