Structure and Dynamics of Membranes book cover

Structure and Dynamics of Membranes

I. From Cells to Vesicles / II. Generic and Specific Interactions

The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes.

Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Hardbound, 1052 Pages

Published: June 1995

Imprint: North-holland

ISBN: 978-0-444-81975-8

Reviews

  • ... Many of the topics covered here, such as the role of surface tension, the physical basis of the interactions between surfaces and the electrostatic properties of membranes, have not been extensively reviewed elsewhere. ... For those with a more general interest in the properties of membranes, the volume will provide excellent coverage of a less familiar literature.
    SGM Quarterly

Contents

  • Contents: Preface. Part A: 1. Biological membranes architecture and function (E. Sackmann). 2. The evolution of membranes (M. Bloom, O.G. Mouritsen). 3. Polymorphism of lipid-water systems (J.M. Seddon, R.H. Templer). 4. Phospholipid monolayers (H. Mhwald). 5. Physical basis of self-organization and function of membranes: physics of vesicles (E. Sackmann). 6. Lateral diffusion in membranes (P.F.F. Almeida, W.L.C. Vaz). 7. Molecular theory of chain packing, elasticity and lipid-protein interaction in lipid bilayers (A. Ben-Shaul). 8. Morphology of vesicles (U. Seifert, R.Lipowsky). 9. Material transport across permeability barriers by means of lipid vesicles (G. Cevc). 10. Applications of liposomes (D.D. Lasic).Part B: 11. Generic interactions of flexible membranes (R. Lipowsky). 12. Electrostatic properties of membranes: The Poisson-Boltzmann theory (D. Andelman). 13. Interaction in membrane assemblies (V.A. Parsegian, R.P. Rand). 14. Tension-induced mutual adhesion and a conjectured superstructureof lipid membranes (W. Helfrich). 15. Physical actions in biological adhesion (E. Evans). 16. Adhesion of cells (P. Bongrand). 17. Cell membranes and the cytoskeleton (P. Janmey). 18. Electroporation and electrofusion of membranes (D.S. Dimitrov). 19. Cation-induced vesicle fusion modulated by polymersand proteins (K. Arnold). Author index. Subject index.

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