Strategies and Tactics in Organic SynthesisEdited by
- Michael Harmata, University of Missouri, MO, USA
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.
Organic chemists; academic libraries, chemical and pharmaceutical companies
Strategies and Tactics in Organic Synthesis
Hardbound, 536 Pages
Published: December 2007
Imprint: Academic Press
"This book is a chronicle of synthetic problems and strategies written by leading organic chemists, who give their own personal accounts of the practice of organic synthesis. It is part lab. notes and memoir and should be an interesting read for both organic chemistry students and practitioners alike."
J. AM. CHEM. SOC, Vol. 128, no. 10, 2006
- chapter 1 TOTAL SYNTHESIS OF RK-397TOTAL SYNTHESIS OF RK-397chapter 2 A FORMAL TOTAL SYNTHESIS OF THE MARINEDITERPENOID, DIISOCYANOADOCIANEchapter 3 TOTAL SYNTHESES OF ZOAPATANOLchapter 4 SYNTHESIS OF MOLECULAR TWEEZERS ANDCLIPS BY THE USE OF A MOLECULAR LEGO SET AND THEIR SUPRAMOLECULAR FUNCTIONSchapter 5 APPLICATION OF C-GLYCOSIDES IN THE TOTAL SYNTHESIS OF (-)-GAMBIEROLchapter 6 A BIOMIMETIC APPROACH TO THE OCAGLAMIDES EMPLOYING PHOTOGENERATION OF OXIDOPYRYLIUMSDERIVED FROM 3-HYDROXYFLAVONESchapter 7 SYNTHESIS STUDIES OF DOLABELLANES AND TRANSANNULAR PROCESSES LEADING TO RELATED DITERPENESchapter 8 DIPHENYLOXAZINONES: VERSATILE TEMPLATESFOR THE ASYMMETRIC SYNTHESIS OF (-)(-)-AMINO ACIDS, PEPTIDE ISOSTERES, AND NATURAL PRODUCTSchapter 9 RHODIUM-CATALYZED CYCLOISOMERIZATIONREACTIONS OF ALLENES IN DIVERSITY-ORIENTEDSYNTHESISchapter 10 HYDROGEN-BOND-MEDIATED ORGANIC SYNTHESIS IN THE SOLID STATE chapter 11 TOTAL SYNTHESES OF NATURAL PRODUCTSUSING THE COMBINED C(-)(-)H ACTIVATION/COPE REARRANGEMENT AS THE KEY STEPchapter 12 THE TOTAL SYNTHESIS OF AMPHIBIANALKALOIDS USING THE INTRAMOLECULAR SCHMIDT REACTIONchapter 13 SEDUCED BY A SIRENS CALL: EXPANDINGAPPLICATIONS FOR AROMATIC COMPOUNDS AND THE SYNTHESIS OF (+)-RISHIRILIDE B