Spinal Cord Injury book cover

Spinal Cord Injury

Handbook of Clinical Neurology Series

Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury.


Neuroscience and Clinical Neurology research specialists and practicing neurologists.

Hardbound, 656 Pages

Published: November 2012

Imprint: Elsevier

ISBN: 978-0-444-52137-8


  • "Providing the latest information on all aspects of spinal cord injury, this volume supplants a 1992 work published in the Handbook of Clinical Neurology series titled Spinal Cord Trauma. Bridging the gap between bench and bedside, coverage encompasses diagnosis and prognosis; medical, surgical, and rehabilitative management of acute spinal cord injury; therapies for chronic spinal cord injury; and preclinical research."--Reference & Research Book News, October 2013


  • SECTION 1: Developmental and Anatomical Perspectives
    1. Development and maturation of the spinal cord: implications of molecular and genetic defects
          G.W.J. Hawryluk, C.A. Ruff and M.G. Fehlings
    2. Anatomy and biomechanics of the spinal column and cord
         V.J. Miele, M.M. Panjabi and E.C. Benzel
    SECTION 2  Diagnosis and Prognosis
    3. Clinical diagnosis and prognosis following spinal cord injury
         A.S. Burns, R.J. Marino, A.E. Flanders and H. Flett
    4. Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury
        A.Curt and P.H. Ellaway
    5. Concepts of aging with paralysis: implications for recovery and treatment
         M. Wirz and V. Dietz
    6. Advanced MRI strategies for assessing spinal cord injury
         S.A. Smith, J.J. Pekar and P.C.M. van Zijl
    SECTION 3  Acute spinal cord injury: medical, surgical and rehabilitative management
    7. Advances in the management of spinal cord and spinal column injuries
         A. Taghva, D.J. Hoh and C.L. Lauryssen
    8. Spinal cord injuries in children and adolescents
        L.C. Vogel, R.R. Betz and M.J. Mulcahey
    9. The changing landscape of spinal cord injury
         N. Juknis, J.M. Cooper and O. Volshteyn
    10. Surgical treatments to restore function control in spinal cord injury
           M.W. Keith and A. Peljovich
    11. Advances in the rehabilitation management of acute spinal cord injury
          J.F. Ditunno, D.D. Cardenas, C. Formal and K. Dalal
    12. Spasticity
           V. Dietz and T. Sinkjaer
    13. Disordered cardiovascular control after spinal cord injury
           L.C. Weaver, J.C. Fleming, C.J. Mathias and A.V. Krassioukov
    14. New concepts in the prevention of pressure sores
          K. Bogie, H.L. Powell and C.H. Ho
    15. Functional electrical stimulation for bladder, bowel and sexual function
           G.H. Creasey and M.D. Craggs
    16. Evidence based therapy for recovery of function after spinal cord injury
          S. Harkema, A. Behrman and H. Barbeau
    17. Functional electrical stimulation: restoration of respiratory function
           R.P. Onders
    18. Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord
           C.H. Tator, K. Minassian and V.K. Mushahwar
    19. Promoting optimal functioning in spinal cord injury: the role of rehabilitation
          S.T. Wegener, L.L. Adams and D. Rohe
    SECTION 4  Chronic spinal cord injury - the changing perspective of neurorestorative rehabilitation, activity-based and surgical restoration therapies
    20. The changing field of rehabilitation: optimizing spontaneous regeneration and functional
           J.W. McDonald III, C.L. Sadowsky and A. Stampas
    21. The longitudinal spinal cord injury: lessons from intra spinal plexus, cauda equina and
           medullary conus lesions
           T. Carlstedt and L. Havtorn
    22. Post-traumatic syringomyelia
          C.B. Shields, Y.P. Zhang and L.B.E. Shields
    23. Post-traumatic deformity: prevention and management
          J. Wilson and J.M. Buchowski
    SECTION 5  Preclinical research - bridging the gap between bench and bedside
    24. Spinal cord injury clinical trials: translational process, review of past and proposed acute
          trials with reference to recommended trial guidelines
           J. Steeves and A. Blight
    25. Translating preclinical approaches into human application
           V. Dietz and A. Curt
    26. Translational spinal cord injury research: preclinical guidelines and challenges
           P.J. Reier, M.A. Lane, E.D. Hall, Y.D. Teng and D.R. Howland
    27. Brain-machine interfaces and transcranial stimulation: future implications for directing
          functional movement and improving function after spinal injury in humans
          J.M. Carmena and L.G. Cohen
    28. Approaches to repairing the damaged spinal cord: overview
           D. Becker and J.W. McDonald III
    29. Limiting spinal cord injury by pharmacological intervention
          J.V. Priestley, A.T. Michael-Titus and W. Tetzlaff
    30. Harmful and beneficial effects of inflammation after spinal cord injury: potential
          therapeutic implications
           S. David, R. López-Vales and V.W. Yong
    31. Defeating inhibition of regeneration by scar and myelin components
           J.W. Fawcett, M.E. Schwab, L. Montani, N., Brazda and H.W. Müller
    32. Realising the maximum potential of Schwann cells to promote recovery from spinal cord
           M.B. Bunge and P. McGhee Wood
    33. Repair of CNS lesions by transplantation of olfactory ensheathing cells
          G. Raisman, S.C. Barnett and A. R amón-Cueto
    34. Cell transplantation: stem cells and precursor cells
           Q. Cao and S.R. Whittemore
    35. Gene therapy, neurotrophic factors and spinal cord regeneration
           A. Blesch, I. Fischer and M.H. Tuszynski
    36. Scaffolds to promote spinal cord regeneration
           S. Sakiyama-Elbert, P.J. Johnson, S.I. Hodgetts, G.W. Plant and A.R. Harvey
    37. Molecular target discovery for neural repair in the functional genomics era
           J. Verhaagen, R.E. van Kesteren, K.A.M. Bossers, H.D. MacGillavry, M.R. Mason and
          A.B. Smit
    38. Combination therapies
           M. Oudega, E.J. Bradbury and M.S. Ramer


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