Sleep Disorders Part I book cover

Sleep Disorders Part I

Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)

Sleep Disorders Part 1 offers a glimpse of developments that focus on diagnostic techniques in the field of neurobiology of sleep. This part discusses the models of the rapid eye movement (REM) sleep mechanism; issues regarding sleep states, stages, and memory consolidation; and advances in the understanding of the sleep-wake genes, gene products, the circadian clock, and the role of sleep duration. This book explains noninvasive neuroimaging studies, particularly positron emission tomographic and single photon emission computed tomographic scans. It further discusses advances in clinical science, including concepts about neurobiology of sleep, narcolepsy-cataplexy, therapy, and laboratory techniques. The significant advances in therapy have led to the addition of new drugs for the treatment of different sleeping disorders, as described in this book. Sleep is essential to humans. Awareness of its true importance leads to the development and acceptance of sleep medicines in the market.

Neuroscience research workers

Hardbound, 720 Pages

Published: December 2010

Imprint: Elsevier

ISBN: 978-0-444-52006-7


  • Foreword



    List of contributors

    Section 1 History of sleep medicine

        1. History of sleep medicine

    Section 2 Basic science and methods

        2. Normal sleep-recording and scoring techniques

        3. Assessment of daytime sleepiness

        4. Actigraphic monitoring of sleep and circadian rhythms

        5. Video recordings and video polysomnography

        6. Functional neuroimaging in sleep, sleep deprivation, and sleep disorders

    Section 3 Basic mechanisms of sleep

        7. The phylogeny of sleep

        8. Ontogeny of EEG sleep from neonatal through infancy periods

        9. Neurobiology of waking and sleeping

        10. Neurobiology of REM sleep

        11. Neurochemistry of sleep: an overview of animal experimental work

        12. Molecular neurobiology of sleep

        13. Manifestations and functional implications of sleep homeostasis

        14. Thermoregulation in wakefulness and sleep in humans

        15. Cytokines in immune function and sleep regulation

        16. Endocrine and metabolic changes during sleep

        17. Sleep, memory, and molecular neurobiology

    Section 4 Clinical aspects of sleep disorders

        18. Epidemiology of sleep disorders

        19. Cardiovascular and cerebrovascular physiology in sleep

        20. Cardiovascular diseases and sleep apnea

        21. Alterations in gastrointestinal functioning during sleep

        22. Sleep and genitourinary systems: physiology and disorders

        23. Sleep enuresis

        24. Respiratory physiology in sleep and wakefulness

        25. Obstructive sleep apnea: diagnosis, risk factors, and pathophysiology

        26. Upper-airway resistance syndrome

        27. Central sleep apnea

        28. Positive-pressure treatment of obstructive sleep apnea syndrome

        29. Medical and surgical treatment of obstructive sleep apnea syndrome, including dental appliances

        30. Noninvasive positive ventilation in the treatment of sleep-related breathing disorders

        31. Sleep and pulmonary diseases

        32. Sleep-associated respiratory disorders and their psychobehavioral consequences in children

        33. Sudden death in infants during sleep

        34. Neurobiology and the neurological basis of dreaming

        35. Abnormal dreams and nightmare disorders

        36. Sleep and psychiatric diseases

        37. Sleep-related eating disorder

        38. Alcohol, toxins, and medications as a cause of sleep dysfunction

        39. Sleep, pain, fibromyalgia, and chronic fatigue syndrome

        40. Women and sleep

        41. Normal and abnormal sleep in the elderly



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