Save up to 30% on Elsevier print and eBooks with free shipping. No promo code needed.
Save up to 30% on print and eBooks.
Single Molecule Biology
1st Edition - October 29, 2008
Editor: Alexander E. Knight
Language: English
Hardback ISBN:9780123742278
9 7 8 - 0 - 1 2 - 3 7 4 2 2 7 - 8
eBook ISBN:9780080921235
9 7 8 - 0 - 0 8 - 0 9 2 1 2 3 - 5
Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological…Read more
Purchase options
LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective.The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery.
Organized by biological system or molecule
Each chapter discusses insights into mechanism of action, structure, and function
Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc
Includes an introduction to key principles and an historical overview
Discusses applications in molecular diagnostics and drug discovery
Provides an expert's perspective on future development
workers from a broad range of disciplines, including structural biologists, biophysicists, cell biologists, and biochemists, advanced undergraduates, graduates, postgraduates, and researchers
Introduction and Historical Perspective Motor Proteins: Linear Motors Actin and Tubulin-Based Motors DNA Motors Rotary Motors Single Molecule Enzymology Ribozymes Ribosomes Large Complexes Membrane Proteins Channels and Pores Cytoskeleton DNA Mechanics and Structure Single Molecules in Cells Hair Cells Structure of Single Protein Molecules Single Molecule Mechanical Properties Single Molecule Applications: Diagnostics Single Molecule Applications: Arrays Single Molecule Applications: Drug Discovery