Silk Biomaterials for Tissue Engineering and Regenerative Medicine

Edited by

  • Subhas Kundu, Indian Institute of Technology Kharagpar, India

Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area.

Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering.

Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering.

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Scientists and engineers working with silk protein based materials; Biomedical engineers and material scientists working in biological materials and biomaterials


Book information

  • Published: March 2014
  • Imprint: Woodhead Publishing
  • ISBN: 978-0-85709-699-9

Table of Contents

Part 1 Fundamentals, processing and types of silk biomaterials
Introduction to silk biomaterials
D. Naskar, R. R. Barua, A. K. Ghosh and S. C. Kundu, Indian Institute of Technology Kharagpur, India
Applications of silk biomaterials in tissue engineering and regenerative medicine
S. Das and U. Bora, Indian Institute of Technology Guwahati, India and B. Borthakur, the Dr. B. Borooah Cancer Institute, India and Indian Institute of Technology Guwahati, India
Processing of Bombyx mori silk for biomedical applications
B. D. Lawrence, Seryx Biomedical Inc., USA
Silk nanostructures based on natural and engineered self-assembly
N. E. Kurland, D. L. Presnall and V. K. Yadavalli, Virginia Commonwealth University, USA
Electropsun silk sericinnanofibers for biomedical applications
M. R. Khan, University of Manitoba, Canada and M. Tsukada, Shinshu University, Japan
Silk fibroin microfiber and nanofiber scaffolds for tissue engineering and regeneration
G. Freddi, Innovhub-Stazioni Sperimentali per l'Industria, Italy and U. Armato, University of Verona Medical School, Italy
Silk powder for regenerative medicine
R. Rajkhowa, Deakin University, Australia and X. Wang, Wuhan Textile University, China
Part 2 Properties and behaviour of silk biomaterials
Biochemical and biophysical properties of native Bombyx mori silk for tissue engineering applications
A. R. Murphy and I. S. Romero, Western Washington University, USA
Structure and properties of spider and silkworm silk for tissue scaffolds
G. Guinea, Universidad Politécnica de Madrid, Spain
Types and properties of non-mulberry silk biomaterials for tissue engineering applications
S. Jasmine and B. B. Mandal, Indian Institute of Technology Guwahati, India
Bio-response to silk sericin
P. Aramwit, Chulalongkorn University, Thailand
Biodegradation behaviour of silk biomaterials
M. Li and J. Li, Soochow University, China
Capillary growth behaviour in porous silk films
L. Bai, Soochow University, China and Shinshu University, Japan
Part 3 Tissue engineering, regenerative medicine and biomedical applications of silk biomaterials
Silk biomaterials for intervertebral disc (IVD) tissue engineering
M. Bhattacharjee and S. Ghosh, Indian Institute Of Technology Delhi, India
Silk scaffolds for dental tissue engineering
S. K. Jindal, Kings College Dental Institute, UK, M. Kiamehr, University of Leeds, UK, W. Sun, Nanjing University Medical School, China and Nanjing-Leeds Joint Center for Oral Health Science, China, and X. B. Yang, University of Leeds, UK, Nanjing-Leeds Joint Center for Oral Health Science, China, and Chapel Allerton Hospital, UK
Silk for cardiac tissue engineering
C. Patra, Max Planck Institute for Heart and Lung Research, Germany and F. B. Engel, University Hospital Erlangen, Germany
Silk for dermal tissue engineering
T. Bayat, University of Manchester, UK and A. Bayat, University of Manchester, UK and South Manchester University Hospital Foundation Trust, UK
Silk scaffolds for 3D tumour modelling
S. Talukdar and S. C. Kundu, Indian Institute of Technology Kharagpur, India
Silk hydrogels for tissue engineering and dual drug delivery
K. Numata, RIKEN, Japan
Silk for pharmaceutical and cosmeceutical applications
J. Wong, H-K. Chan and W. Chrzanowski, University of Sydney, Australia