Silicon Carbide Biotechnology
A Biocompatible Semiconductor for Advanced Biomedical Devices and Applications
By- Stephen Saddow, Department of Electrical Engineering, College of Engineering and Department of Molecular Pharmacology and Physiology, College of Medicine, University of South Florida, Tampa, USA
Silicon Carbide (SiC) is a wide-band-gap semiconductor biocompatible material that has the potential to advance advanced biomedical applications. SiC devices offer higher power densities and lower energy losses, enabling lighter, more compact and higher efficiency products for biocompatible and long-term in vivo applications ranging from heart stent coatings and bone implant scaffolds to neurological implants and sensors.
The main problem facing the medical community today is the lack of biocompatible materials that are also capable of electronic operation. Such devices are currently implemented using silicon technology, which either has to be hermetically sealed so it cannot interact with the body or the material is only stable in vivo for short periods of time.
For long term use (permanent implanted devices such as glucose sensors, brain-machine-interface devices, smart bone and organ implants) a more robust material that the body does not recognize and reject as a foreign (i.e., not organic) material is needed. Silicon Carbide has been proven to be just such a material and will open up a whole new host of fields by allowing the development of advanced biomedical devices never before possible for long-term use in vivo.
This book provides not only the materials and biomedical engineering communities with a seminal reference book on SiC that they can use to further develop the technology, but to also provide a technology resource for medical doctors and practitioners who are hungry to identify and implement advanced engineering solutions to their everyday medical problems that currently lack long term, cost effective solutions.Hardbound, 495 Pages
Published: November 2011
Imprint: Elsevier
ISBN: 978-0-12-385906-8
Contents
1 Silicon Carbide materials growth and processing
2 SiC Synthesis - from amorphous and polycrystalline coatings to single crystal films
3 Multi-functional SiC surfaces: From Passivation to Functionalization
4 SiC in-vitro biocompatibility: skin cells and connective tissues5 SiC hemacompatibility for cardiovascular applications
6 SiC as a long-term implantable neural prosthetic material7 SiC for brain-machine-interfaces
8 SiC for microdialysis9 Biocompatibility of SiC for osteo-applications
10 SiC bioMEMS11 SiC as a bio-compatible marker for disease detection
12 Carbon Electrodes: Graphene and Graphite on SiC

