List of special reviews. How to use this book.Essay: Thirty years of experience of the Boston Collaborative Drug Surveillance Program in relation to principles and methods of drug safety research(H. Jick). Central nervous system stimulants and drugs that suppress appetite (R.P. Sequeira). Antidepressant drug (P.J. Cowen).Lithium (M. Schou).Drugs of abuse (J.K. Patel, E. Wong, A.I. Green). Hypnotics and sedatives (S. Curran, S. Lally).Antipsychotic drugs (A. Carvajal, L.H. Martin Arias).Antiepileptic drugs (E. Perucca).Opioid analgesics and narcotic antagonists (A.H. Ghodse, R.E. Edwards). Anti-inflammatory and antipyretic analgesics and drugs used in gout (A. Del Favero).General anesthetics and therapeutic gases (T.G. Short, E. Petcu).Local anesthetics (S. Schug, J. Thomas). Neuromuscular blocking agents and skeletal muscle relaxants (M. Leuwer, O. Zuzan). Drugs affecting autonomic functions or the extrapyramidal system (M. Schachter).Dermatological drugs, topical agents, and cosmetics (A.C. de Groot).Antihistamines (L. Turner).Drugs acting on the respiratory tract (J.W. Paterson, K.M. Lulich). Positive inotropic drugs and drugs used in dysrhythmias (J.K. Aronson).Beta-adrenoceptor antagonists and antianginal drugs (A.P. Maggioni, M.G. Franzosi, R. Latini).Drugs acting on the cerebral and peripheral circulations (R. Verhaeghe).Antihypertensive drugs (F. Zannad).Diuretics (G.T. McInnes).Metals (G.B. van der Voet, F.A de Wolff).Metal antagonists (R.H.B. Meyboom).Antiseptic drugs and disinfectants (P. Magee). Penicillins, cephalosporins, other ß-lactam antibiotics and tetracyclines (T. Midtvedt).Miscellaneous antibacterial drugs (S.H. Khoo, T. Walley).Antifungal drugs (R.G. Irwin, A. Groll, T.J. Walsh). Antiprotozoal drugs (S. Krishna, R. Price, I. Ribeiro).Antiviral drugs (P. Reiss, M.D. de Jong).Drugs used in tuberculosis and leprosy (C.J. Ellis).Antihelminthic drugs (A.G.C. Bauer). Vaccines (S. Dittmann).Blood, blood components, plasma, and plasma products (H.W. Eijkhout, W.G. van Aken).Intravenous infusions - solutions and emulsions (P.I. Folb).Drugs affecting blood coagulation, fibrinolysis and hemostasis (K. Peerlinck, J. Vermylen).Gastrointestinal drugs (R.E. Pounder). Drugs acting on the immune system (T. Vial, G. Chevrel, J. Descotes).Vitamins (H.D. Reuter).Corticotrophins, corticosteroids and prostaglandins (J. Costa, M. Farre).Sex hormones and related compounds, including hormonal contraceptives (A. Buitenhuis, C.J. van Boxtel). Thyroid hormones and antithyroid drugs (J.A. Franklyn).Insulin, glucagon, and oral hypoglycemic drugs (H.M.J. Krans).Miscellaneous hormones (P. Coates).Drugs affecting lipid metabolism (I. Aursnes).Cytostatics and immunosuppressive drugs (A. Stanley). Radiological contrast agents (P. Dawson). Drugs used in ocular treatment (B.C.P. Polak).Treatments used in complementary medicine (E. Ernst, J. Barnes). Miscellaneous drugs, materials and medical devices (N.H. Choulis).International drug monitoring. Address list of national centers participating in the WHO drug monitoring scheme. Index of drugs. Index of side effects.