RNA - Ligand Interactions, Part A: Structural Biology Methods book cover

RNA - Ligand Interactions, Part A: Structural Biology Methods

RNA-Ligand Interactions, Part A focuses on structural biology methods. Major topics covered include semisynthetic methodologies (RNA synthetic methods and derivatization of RNA); RNA structure determination (X-ray crystallography, NMR, EM); techniques for monitoring RNA conformation and dynamics (solution methods and electrophoretic and spectroscopic methods); and modeling tertiary structure: Part B, its companion Volume 318 of Methods in Enzymology, focuses on molecular biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the Series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Biochemists, molecular biologists, geneticists, cell biologists, and microbiologists.

Included in series
Methods in Enzymology


Published: May 2000

Imprint: Academic Press

ISBN: 978-0-12-182218-7


  • "The Methods in Enzymology series represents the gold-standard."
    Praise for the Series, --NEUROSCIENCE

    "Incomparably useful."
    "It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
    "The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
    "The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
    "If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
    "A series that has established itself as a definitive reference for biochemists."


  • Semisynthetic Methodologies:RNA Synthetic Methods.Derivation of RNA.RNA Structure Determination:X-Ray Crystallography.Nuclear Magnetic Resonance Spectroscopy.Electron Microscopy.Techniques for Monitoring RNA Conformation and Dynamics:Solution Methods.Electrophoretic and Spectroscopic Methods.Modeling Tertiary Structure.Author Index.Subject Index.


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