Red Cell Development

Current Topics in Developmental Biology

Edited by

  • James Bieker, Mount Sinai School of Medicine, Department of Molecular, Cell & Developmental Biology, New York, NY, USA

This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume.
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developmental biologists, molecular biologists, stem cell biologists, pediatric and adult hematologists


Book information

  • Published: February 2008
  • ISBN: 978-0-12-374366-4

Table of Contents

1 Ontogeny of Erythropoiesis in the Mammalian EmbryoKathleen McGrath and James Palis2 The Erythroblastic IslandDeepa Manwani and James J Bieker3 Epigenetic Control of Complex Loci During ErythropoiesisRyan J. Wozniak and Emery H. Bresnick4 The Role of the Epigenetic Signal, DNA Methylation, in Gene Regulation During Erythroid DevelopmentGordon D. Ginder, Merlin N. Gnanapragasam, and Omar Y. Mian5 Three-dimensional Organisation of Gene Expression in Erythroid CellsWouter de Laat, Petra Klous, Jurgen Kooren, Daan Noordermeer, Robert-Jan Palstra, Marieke Simonis, Erik Splinter, Frank Grosveld6. Iron Homeostasis and ErythropoiesisDiedra M. Wrighting and Nancy C. Andrews7. The Effects of Nitric Oxide on Red Cell Development and PhenotypeVladan P. Èokiæ and Alan N. Schechter8. Diamond Blackfan Anemia: A Disorder of Red Blood Cell DevelopmentSteven. R. Ellis and Jeffrey M. Lipton