Recent Advances in Parkinsons Disease
Part II: Translational and Clinical Research
- Anders Bjorklund
- Angela Cenci-Nilsson
This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles.
Audience
Neuroscientists, psychologists, neurologists
Included in series
Progress in Brain Research
Progress in Brain Research
Hardbound, 368 Pages
Published: October 2010
Imprint: Elsevier
ISBN: 978-0-444-53750-8
Contents
Section I: Animal models of PD
- What have we learned from Drosophila Models of Parkinson's Disease? - Ming Guo
- Neurotoxic in vivo models of Parkinsons disease: recent advances - Timothy Greenamyre & Jason R. Cannon
- Behavioural analysis of motor and non-motor symptoms in rodent models of Parkinsons disease - Stephen B. Dunnett & Mariah Lelos
- Genetic mouse models of Parkinsons disease: the state of the art - Marie-Francoise Chesselet & Iddo Magen
- Viral vector mediated overexpression of a-synuclein as a progressive model of Parkinsons disease - Anders Bjorklund, Ayse Ulusoy, Mickael Decressac, Deniz Kirik
- Modelling inflammatory pathogenesis of Parkinson's Disease - Malu Tansey & Christopher J. Barnum
- The MPTP-lesioned non-human primate models of Parkinsons disease. Past, present and future - Susan Fox & Jonathan Brotchie
- Abnormal Metabolic Brain Networks in Parkinsons Disease: From Blackboard to Bedside - David Eidelberg & Chris C. Tang
- Imaging the Nigrostriatal System to Monitor Disease Progression and Treatment-Induced Complications - Jon Stoessl & Renju Kuriakose
- Brain imaging after neural transplantation - Paola Piccini & Marios Politis
- Imaging non-motor aspects of Parkinsons disease - David Brooks & Nicola Pavese Section III: Frontiers in PD treatment
- Gene therapy for dopamine replacement - Deniz Kirik & Tomas Björklund, Erik Ahlm Cederfjäll
- Neurotrophic Factor Therapy for Parkinsons disease - Jeffrey Kordower, Rangasamy Suresh Babu, Katherine Soderstrom, Roy A.E. Bakay
- Neural grafting in Parkinsons disease: Problems and possibilities - Patrik Brundin, Roger A Barker and Malin Parmar
- Neural grafting in Parkinson´s disease: Unraveling the mechanisms underlying graft-induced dyskinesia - Emma L Lane, Anders Björklund, Stephen B Dunnett, Christian Winkler
- Deep Brain Stimulation: State of the Art and Novel Stimulation Targets - Andres Lozano & Francisco A. Ponce
- The challenge of Non-Motor Symptoms in Parkinson´s Disease - Ray Chaudhuri & Per Odin
Section II: Exploring PD with brain imaging
