Rang & Dale's Pharmacology

With STUDENT CONSULT Online Access

By

  • Humphrey Rang, MB BS MA DPhil Hon FBPharmacolS FMedSci FRS , Emeritus Professor of Pharmacology, University College London, London, UK
  • James Ritter, DPhil FRCP FBPharmacolS FMedSci, Emeritus Professor of Clinical Pharmacology, King's College London, and Medical Research Director, Quintiles, London, UK
  • Rod Flower, PhD DSc FBPharmacolS FMedSci FRS, Professor, Biochemical Pharmacology, The William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London , London, UK

A straightforward way to master a complex subject! This bestselling textbook presents all the knowledge you need to get through your pharmacology course and beyond—using a clear and accessible approach that makes the material easy and interesting to learn. Progressing logically from a molecular understanding of receptors and drug actions to the clinical uses of the most important groups of drugs, it delivers the latest information on cannabinoids and rimonabant, Cox 2 inhibitors, pharmacogenetics, biopharmaceuticals, and drug abuse—as well as "lifestyle drugs" such as performance-enhancing substances, botulinum toxin, and Viagra®. And now, online access via STUDENT CONSULT makes it an even more effective learning resource!
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Audience

Medical and Undergraduate students studying Pharmacology, Pharmacy students

 

Book information

  • Published: January 2007
  • Imprint: CHURCHILL LIVINGSTONE
  • ISBN: 978-0-7020-4074-0


Table of Contents

Section 1. General Principles

1. What is pharmacology?

2. How drugs act: general principles

3. How drugs act: molecular aspects

4. Cellular mechanisms: excitation, contraction and secretion

5. Cellular mechanisms: cell proliferation and apoptosis

6. Method and measurement in pharmacology

7. Absorption and distribution of drugs

8. Drug elimination and pharmacokinetics


Section 2. Chemical Mediators

9. Chemical mediators and the autonomic nervous system

10. Cholinergic transmission

11. Noradrenergic transmission

12. Other peripheral mediators: 5-hydroxytryptamine and purines

13. Peptides and proteins as mediators

14. Nitric oxide

15. Local hormones, inflammation and immune reactions

16. Anti-inflammatory and immunosuppressant drugs


Section 3. Drugs Affecting Major Organ Systems

17. The heart

18. The vascular system

19. Atherosclerosis and lipoprotein metabolism

20. Haemostasis and thrombosis

21. The heamopoietic system

22. The respiratory system

23. The kidney

24. The gastrointestinal tract

25. The endocrine pancreas and the control of blood glucose

26. Obesity

27. The pituitary and adrenal cortex

28. The thyroid

29. The reproductive system

30. Bone metabolism


Section 4. The Nervous System

31. Chemical transmission and drug action in the central nervous system

32. Amino acid transmitters

33. Other transmitters and modulators

34. Neurodegenerative disorders

35. General anaesthetic agents

36. Anxiolytic and hypnotic drugs

37. Antipsychotic drugs

38. Drugs used in affective disorders

39. Antiepileptic drugs

40. Analgesic drugs

41. CNS stimulants and psychotomimetic drugs

42. Drug dependence and drug abuse

43. Local anaesthetics


Section 5. Drugs Used in the Treatment of Infections and Cancer

44. Basic principles of chemotherapy

45. Antibacterial drugs

46. Antiviral drugs

48. Antiprotozoal drugs

49. Anthelminthic drugs

50. Cancer chemotherapy


Section 6. Special Topics

51. Individual variation and drug interaction

52. Unwanted effects and drug toxicity

53. Lifestyle and non-medical uses of drugs

53. Gene therapy

54. Drug discovery and development


Appendix


Index