Psychophysiological States

The Ultradian Dynamics of Mind-Body Interactions


  • David Shannahoff-Khalsa, University of California, San Diego, USA

Our understanding of psychophysiological states are now more broadly defined by the inclusion of the lateralized ultradian rhythms of the autonomic and central nervous systems (ANS and CNS) that play a key regulatory role in mind-body states. These neural rhythms are a unique step in the evolution of the nervous system that have mostly been ignored or missed in our understanding of physiology, mental activities, brain rhythms, and in the treatment of psychiatric disorders. The multivariate physiological experiments reviewed in this book provide a new “big picture” for how the body’s major systems (ANS, CNS, neuroendocrine, cardiovascular, fuel-regulatory, gastrointestinal, immune) are regulated, integrated, and coordinated by the ANS via the hypothalamus during both waking and sleep. This discovery has implications for psychiatrists, psychologists, stress physiologists, cardiologists, sleep researchers, neuroscientists, neuroendocrinologists, cognitive scientists, and those interested in performance, anxiety, depression, schizophrenia, autism, and addictive and impulse control disorders. This book includes the translational neuroscience aspect of this discovery, including implications for vagal nerve stimulation studies.
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Neuroscientists, psychiatrists, chronobiologists, physiologists, psychophysiologists, cognitive neuroscientists, therapists, sleep researchers, stress physiologists, and addiction specialists.


Book information

  • Published: November 2007
  • ISBN: 978-0-12-374275-9


"[T]his text presents a detailed and highly technical analysis of various ways that physiology overlaps with psychology."--European Association for Body Psychotherapy Newsletter

Table of Contents

Introduction - An Historical Perspective on Psychophysiological StatesI. Towards an Integration of the Temporal and Structural Organization of Higher Vertebrates: Lateralized Ultradian Rhythms of the Nervous SystemI.A. Lateralized Rhythms of the Autonomic Nervous SystemI.B. Lateralized Rhythms of the Central Nervous System I.B.I. Ultradian Studies of Lateralized EEG During Sleep I.B.2. Ultradian Studies of Lateralized EEG During Waking I.B.3. Ultradian Studies of Lateralized Cognitive Performance Efficiency I.B.4. Studies of Lateralized Cognitive Performance After Awakening from REM and NREM Sleep StagesI.C. Ultradian Rhythms of the Cardiovascular, Neuroendocrine, Fuel-Regulatory, Gastrointestinal, and Immune SystemsI.D. Hypothalamic Regulation and Integration of the ANS-CNS Rhythm and the Basic Rest Activity CycleI.E. Ultradian Rhythms in Arousal, Performance, and BehaviorII. A Neural Matrix for Coupling Mind and MetabolismIII. A Pendulum of ANS-CNS Activities and Homeostasis: A New Paradigm for Stress and DiseaseIV. Implications of Lateralized Rhythms for Adaptation and HomeostasisV. Implications of Lateralized Rhythms for Psychopathology A. Anxiety B. Depression C. SchizophreniaVI. Translational Elements of Psychophysiological States: Regulation of Lateralized Autonomic and Central Nervous System Activities VI.A. Vagal Nerve Stimulation VI.A.1. Cognitive Abilities VI.B.2. Autonomic Physiology VI.B. Unilateral Forced Nostril Breathing VI.A.1. Cognitive Abilities VI.B.2. Autonomic Physiology VII. ConclusionVIII. References