Proteome Characterization and Proteomics

Edited by

  • Timothy Veenstra, National Cancer Institute at Frederick, Frederick, Maryland
  • Richard Smith, Pacific Northwest National Laboratory, Richland, Washington

The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies.
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Biochemists, molecular, cell and developmental biologists, geneticists, biophysicists, and biomedical researchers


Book information

  • Published: August 2003
  • ISBN: 978-0-12-034265-5


PRAISE FOR THE SERIES "Proteome Characterization and Proteomics delivers and excellent balance of state-of-the-art technologies, chemistries, and instrumentation designed to measure proteomes...Overall, this is a well-written volume on the current state of proteome technologies. The editors convey an understanding of the latest developments in mass spectrometry, protein fractionation and applications." -Environmental Health Perspective, August 2004 "The authority, originality, and editing of the reviews are first class." —NATURE "The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." —JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Table of Contents

Proteomics in the Postgenomic AgeThe Tools of ProteomicsProteomic Analysis by Two-Dimensional Polyacrylamide Gel ElectrophoresisHigh Perfoemance Seperations and Mass Spectrometric Methods for High Throughput Proteomics Using Accurate Mass TagsCurrent Strategie for Quantitative ProteomicsProteome Analysis of Posttranslational ModificationsMapping Prtein Modifications with LC-MS and the SALSA AlgorithmEmerging Role of Mass Spectrometry in Structural and Functional ProteomicsThe Role of Seperation Science in Proteomics ResearchProteomics of Membrane ProteinsProteomics in Drug DiscoveryFrom Clone to Crystal: Maximizing the Amount of Protein Samples for Structure DeterminationProteomics and Bioinformatics