Protein Phosphorylation in Health and Disease book cover

Protein Phosphorylation in Health and Disease

This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields.

Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Hardbound, 446 Pages

Published: February 2012

Imprint: Academic Press

ISBN: 978-0-12-396456-4


    "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal


    1. Wip1 -dependent signaling pathways in health and diseases
      Yun-hua Zhu and Dmitry V. Bulavin
    2. HijAkt: The PI3k/Akt pathway in virus replication and pathogenesis
      Ewan F. Dunn and John H. Connor
    3. Phosphoproteins in stress-induced disease
      Lucy E. Dalton, Eleanor Healey, James Irving & Stefan J. Marciniak
    4. G-substrate: The Cerebellum and Beyond
      Shogo Endo
    5. Targeting Phosphorylation of Eukaryotic Initiation Factor-2a to Treat Human Disease
      Melissa J. Fullwood, Wei Zhou and Shirish Shenolikar
    6. Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia
      Jean-Antoine Girault
    7. The Role of Protein Phosphorylation in Therapy-resistance and Disease Progression in Chronic Myelogenous Leukemia
      Wen Chun JUAN and S. Tiong ONG
    8. Phosphatases driving mitosis: pushing the gas and lifting the brakes
      Erika Segear Johnson and Sally Kornbluth
    9. Protein tyrosine phosphatases in cancer: Friends and Foes
      David P. Labbé, Serge Hardy, Michel L. Tremblay
    10. Multiple Roles Of Stat3 In Cardiovascular Inflammatory Responses
      Cheh Peng Lim and Xin-Yuan Fu
    11. PAKs in human disease
      Perry M. Chan and Ed Manser
    12. Protein Phosphatases and Alzheimer’s Disease
      Steven P. Braithwaite, Jeffry B. Stock, Paul J. Lombroso, Angus C. Nairn
    13. Role of the JNK pathway in human diseases
      Kanaga Sabapathy
    14. Mass spectrometric tools for systematic analysis of protein phosphorylation
      Nicole St-Denis1 and Anne-Claude Gingras


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