Progress in Medicinal Chemistry

Edited by

  • F.D. King, GlaxoSmithKline, Harlow, Essex, UK
  • G. Lawton, St. Ippolyts, Herts, UK

The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a ‘quality lead’, where these ‘quality leads’ come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis.
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Audience

Chemists, biologists, doctors, pharmacists and anyone interested in the contemporary controversy about drugs, drug firms, and the community

 

Book information

  • Published: February 2007
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-52808-7


Table of Contents

PrefaceList of ContributorsHit and Lead Identification: Efficient practices for drug discoveryDPPIV Inhibition: Promising Therapy for the Treatment of Type 2 DiabetesRecent Progress Towards Nonpeptide Ligands for the Melanocortin-4 ReceptorTuberculosis chemotherapy: recent developments and future perspectivesSubject IndexAuthor Index (Volumes 1-45)Subject Index (Volumes 1-45)