Progress in Medicinal ChemistrySeries Editor:
- F.D. King, GlaxoSmithKline, Harlow, Essex, UK
- G. Lawton, St. Ippolyts, Herts, UK
The Progress in Medicinal Chemistry series spans a wide range of topics of interest to the drug discovery community. This particular volume touches upon the following:* The Herg ion channel * Fluorescence-based high throughput assay * Aprepitant and neurokinin receptors * Muscarinic receptor targets * Gene activation pathways * Malaria and antimalarial drugs * HIV virus mutation and new therapeutics Progress in Medicinal Chemistry is available online on ScienceDirect full-text online of volumes 41 onwards.
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Chemists, biologists, doctors, pharmacists and anyone interested in the contemporary controversy about drugs, drug firms, and the community
Progress in Medicinal Chemistry
Hardbound, 302 Pages
Published: April 2005
- Preface1. Human Ether-a-go-go Related Gene (Herg): A Chemist's Perspective 2. Fluorescence Based Assays3. Selective and Combined Neurokinin Receptor Antagonists4. Muscarinic Receptor Subtype Pharmacology and Physiology5. The Transcription Factor NF-êB as Drug Target6. Recent Advances in the Search for New Antimarial Agents7. The Discovery of the CCR5 Receptor Antagonist UK-427857. A new agent for the Treatment of HIV infection and AIDS