Progress in Medicinal ChemistrySeries Editor:
- F.D. King
- G. Lawton
The Progress in Medicinal Chemistry series spans a wide range of topics of interest to the drug discovery community. This particular volume touches upon the following:* The Herg ion channel * Fluorescence-based high throughput assay * Aprepitant and neurokinin receptors * Muscarinic receptor targets * Gene activation pathways * Malaria and antimalarial drugs * HIV virus mutation and new therapeutics Progress in Medicinal Chemistry is available online on ScienceDirect full-text online of volumes 41 onwards.
Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elseviers extensive researcher network.
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Chemists, biologists, doctors, pharmacists and anyone interested in the contemporary controversy about drugs, drug firms, and the community
Progress in Medicinal Chemistry
Hardbound, 302 Pages
Published: April 2005
se for the Series: "...may the Progress in Medicinal Chemistry series continue its invaluable service..."
--Chemistry and Industry
... a valuable source of reference"
--British Medical Journal
...These volumes should be on the shelves of all specialist libraries which claim to cater for chemists, biologists, doctors and pharmacists and should be available to everyone interested in the contemporary controversy about drugs, drug firms and the community."
...the consistently high standards for this series have been maintained in the present volume. This volume should certainly take its place next to the previous volumes in this series in libraries devoted to medicinal chemistry and drug research..."
--Journal of Medicinal Chemistry
- Preface1. Human Ether-a-go-go Related Gene (Herg): A Chemist's Perspective 2. Fluorescence Based Assays3. Selective and Combined Neurokinin Receptor Antagonists4. Muscarinic Receptor Subtype Pharmacology and Physiology5. The Transcription Factor NF-êB as Drug Target6. Recent Advances in the Search for New Antimarial Agents7. The Discovery of the CCR5 Receptor Antagonist UK-427857. A new agent for the Treatment of HIV infection and AIDS