- Byron Caughey, Rocky Mountain Laboratories, Montana, U.S.A.
Prion Proteins is "issue-oriented" and edited by a well-known authority in the field. Topics covered include structure, diversity, and energetics as well as the diseases associated with prion proteins.View full description
Biochemists, neurochemists, molecular biologists, biophysicists, and biomedical researchers.
- Published: June 2001
- Imprint: ACADEMIC PRESS
- ISBN: 978-0-12-034257-0
"...all thinkable aspects of prion-protein biochemistry are dissected, largely by the field's best experts. ...I enjoyed the book, and have learned quite a few things about modern methods of protein analysis. Investigators with a background in protein chemistry who wish to enter the prion field, as well as prionologists who desire to deepen their knowledge of prion biophysics, will find many aspects of this book stimulating and informative."
--Adriano Aguzzi, Institute of Neuropathology, University Hospital of Zurich, in NATURE CELL BIOLOGY (March 2002)
"This appears to be the first comprehensive review of various aspects of prion biochemistry/biology. As such, it is a welcome addition."--Eugene A. Davidson in DOODY'S PUBLISHING (October 2001)
Table of ContentsPreface.Prion Protein Diversity and Disease in the Transmissible Spongiform Encephalopathies,S.A. Priola.Mass Spectrometric Analysis of Prion Proteins, M.A. Baldwin.Three-Dimensional Structures of Prion Proteins, K. Wuthrich and R. Riek.Folding Dynamics and Energetics of Recombinant Prion Proteins, R. Glockshuber.Simulations and Computational Analyses of Prion Protein Conformations, D.O.V. Alonso and V. Daggett.Interactions and Conversions of Prion Protein Isoforms, B. Caughey, G.J. Raymond, M.A. Callahan, C. Wong, G.S. Baron, and L. Xiong.Studies of Peptide Fragments of Prion Proteins, F.Tagliavini, G. Forloni, P. D'Ursi, O. Bugiani, and M. Salmona.Biosynthesis and Cellular Processing of the Prion Protein, D.A. Harris.Interaction of Prion Proteins with Cell Surface Receptors, Molecular Chaperones, and Other Molecules, S. Gauzynski, C. Hundt, C. Leucht, and S. Weiss.Transgenic Studies of the Influence of the PrP Structure on TSE Diseases, E.A Asante and J. Collinge.Yeast Prions Act as Genes Composed of Self-Propagating Protein Amyloids, R.B. Wickner, K.L. Taylor, H.K. Edkes, M. Maddeleis, H. Moriyama, and B.T. Roberts.[PSI+], SUP35, and Chaperones, T.R. Serio and S.L. Lindquist.Author Index.Subject Index.