Preface.Prion Protein Diversity and Disease in the Transmissible Spongiform Encephalopathies,S.A. Priola.Mass Spectrometric Analysis of Prion Proteins, M.A. Baldwin.Three-Dimensional Structures of Prion Proteins, K. Wuthrich and R. Riek.Folding Dynamics and Energetics of Recombinant Prion Proteins, R. Glockshuber.Simulations and Computational Analyses of Prion Protein Conformations, D.O.V. Alonso and V. Daggett.Interactions and Conversions of Prion Protein Isoforms, B. Caughey, G.J. Raymond, M.A. Callahan, C. Wong, G.S. Baron, and L. Xiong.Studies of Peptide Fragments of Prion Proteins, F.Tagliavini, G. Forloni, P. D'Ursi, O. Bugiani, and M. Salmona.Biosynthesis and Cellular Processing of the Prion Protein, D.A. Harris.Interaction of Prion Proteins with Cell Surface Receptors, Molecular Chaperones, and Other Molecules, S. Gauzynski, C. Hundt, C. Leucht, and S. Weiss.Transgenic Studies of the Influence of the PrP Structure on TSE Diseases, E.A Asante and J. Collinge.Yeast Prions Act as Genes Composed of Self-Propagating Protein Amyloids, R.B. Wickner, K.L. Taylor, H.K. Edkes, M. Maddeleis, H. Moriyama, and B.T. Roberts.[PSI+], SUP35, and Chaperones, T.R. Serio and S.L. Lindquist.Author Index.Subject Index.