Principles and Practice of Sleep Medicine book cover

Principles and Practice of Sleep Medicine

This authoritative guide to sleep medicine is also available as an e-dition, book (ISBN: 1416003207) plus updated online reference!

The new edition of this definitive resource has been completely revised and updated to provide all of the latest scientific and clinical advances. Drs. Kryger, Roth, and Dement—and over 170 international experts—discuss the most recent data, management guidelines, and treatments for a full range of sleep problems. Representing a wide variety of specialties, including pulmonary, neurology, psychiatry, cardiology, internal medicine, otolaryngology, and primary care, this "who's who" of experts delivers the most compelling, readable, and scientifically accurate source of sleep medicine available today.

Pulmonary Medicine and Sleep Medicine, Neurology, Psychiatry


Published: March 2005

Imprint: Saunders

ISBN: 978-0-7216-0797-9


  • "A must-have!"-JAMA- March 2006


  • I. Principles of Sleep Medicine

    Normal Sleep and Its Variations

    1. History of Sleep Physiology and Medicine
    2. Normal Human Sleep: An Overview
    3. Normal Aging
    4. Daytime Sleepiness and Alertness
    5. Acute Sleep Deprivation
    6. Chronic Sleep Deprivation
    7. Phylogeny of Sleep Regulation
    8. Mammalian Sleep
    Sleep Mechanisms
    9. Brain Electrical Activity and Sensory Processing During Waking and Sleep States
    10. REM sleep
    11. Basic Mechanisms of Sleep-Wake States
    12. Control of Motoneurons during sleep
    13. Sleep-Promoting Mechanisms in Mammals
    Physiology in Sleep
    14. Physiologic Regulation in Sleep
    15. Cardiovascular Physiology: Central and Autonomic Regulation
    16. Cardiovascular Physiology: The Peripheral Circulation
    17. Respiratory Physiology: Central Neural Control
    18. Respiratory Physiology: Control of Ventilation
    19. Respiratory Physiology: Breathing in Normal Subjects
    20. Respiratory Physiology: Sleep at High Altitudes
    21. Host Defense
    22. Endocrine Physiology
    23. Gastrointestinal Physiology
    24. Temperature Thermoregulation and Sleep
    25. Neural Mechanisms of Sleep-Related Penile Erections
    26. Master Circadian Clock: Master Circadian Rhythm
    27. Circadian Rhythms in Mammals: Formal Properties and Environmental Influences
    28. Anatomy of the Mammalian Circadian System
    29. Physiology of the Mammalian Circadian System
    30. Molecular Genetic Basis for Mammalian Circadian Rhythms
    31. The Human Circadian Timing System and Sleep-Wake Regulation
    32. Melatonin in the Regulation of Sleep and Circadian Rhythms
    33. Sleep Homeostasis and Models of Sleep Regulation
    34. Interaction of Sleep Homeostasis and Circadian Rhythmicity-- Dependent or Independent Systems?
    35. Circadian Rhythms in Sleepiness, Alertness and Performance
    36. Hypnotic Medications: Mechanisms of Action and Pharmacologic Effects
    37. Clinical Pharmacology of Other Drugs Used as Hypnotics
    38. Wake-Promoting Medications: Basic Mechanisms and Pharmacology
    39. Wake-Promoting Medications: Efficacy and Adverse Effects
    40. Drugs That Disturb Sleep and Wakefulness
    Psychobiology and Dreaming
    41. Introduction to Dreams and their Pathology
    42. The Content of Dreams: Methodologic and Theoretical Implications
    43. Chronobiology of Dreaming
    44. The Neurobiology of Dreaming
    45. Dreaming as a Mood Regulation System in Normal and Abnormal Emotional States
    46. Dreams and Nightmares in Posttraumatic Stress Disorder
    47. Why We Dream

    II. Practice of Sleep Medicine

    Impact, Presentation, Diagnosis

    48. Approach to the Patient with Disordered Sleep
    49. Cardinal Manifestations of Sleep Disorders
    50. Use of Clinical Tools and Tests in Sleep Medicine
    51. Classification of Sleep Disorders
    52. Epidemiology of Sleep Disorders
    53. Sleep Medicine, Public Policy, and Public Health
    Disorders of Chronobiology
    54. Introduction: Disorders of Chronobiology
    55. Sleep Disruption in Jet Lag and Other Circadian Rhythm-Related Disorders
    56. Shift Work: Basic Principles
    57. Managing Work Schedules: An Alertness and Safety Perspective
    58. Circadian Disorders of the Sleep-Wake Cycle
    59. Overview of Insomnia: Definitions, Epidemiology, Differential Diagnosis, and Assessment
    60. Etiology and Pathophysiology of Insomnia
    61. Psychological and Behavioral Treatments for Primary Insomnia
    62. Psychological and Behavioral Treatments for Secondary Insomnias
    63. Pharmacologic Treatment for Primary Insomnia
    Neurological Disorders
    64. Narcolepsy: Pharmacology, Pathophysiology, and Genetic Predisposition
    65. Narcolepsy: Diagnosis and Management
    66. Idiopathic Hypersomnia
    67. Parkinsonism
    68. Sleep and Stroke
    69. Sleep and Neuromuscular Disease
    70. Restless Legs Syndrome and Periodic Limb Movements During Sleep
    71. Alzheimer’s Disease and other Dementias
    72. Epilepsy, Sleep, and Sleep Disorders
    73. Other Neurological Disorders
    74. NREM Sleep-Arousal Parasomnias
    75. REM Sleep Parasomnias
    76. Other Parasomnias
    77. Nightmares and Other Common Dream Disturbances
    78. Disturbed Dreaming in Medical Conditions
    79. Sleep Bruxism
    80. Violent Parasomnias: Forensic Medicine Issues
    Sleep Breathing Disorders
    81. Central Sleep Apnea
    82. Anatomy and Physiology of Upper Airway Obstruction
    83. Snoring and Upper Airway Resistance
    84. Genetics of Obstructive Sleep Apnea
    85. Cognition and Performance in Patients with Obstructive Sleep Apnea-Hypopnea
    86. Sleep Apnea and Metabolic Dysfunction
    87. Clinical Features and Evaluation of Obstructive Sleep Apnea-Hypopnea Syndrome and the Upper Airway Resistance Syndrome
    88. Medical Therapy of Obstructive Sleep Apnea-Hypopnea Syndrome
    89. Continuous Positive Airway Pressure for Obstructive Sleep Apnea-Hypopnea
    90. Surgical Management for Sleep Disordered Breathing
    91.Oral Appliances for Sleep Disordered Breathing
    92. Management of Obstructive Sleep Apnea-Hypopnea Syndrome: Overview
    93. Asthma and Chronic Obstructive Pulmonary Disease
    94.Restrictive Lung Disorders
    95 Nocturnal Noninvasive Positive Pressure Ventilation in the Treatment of Chronic Respiratory Failure
    Cardiovascular Disorders
    96. Sleep and Cardiovascular Disease: Present and Future
    97. Sleep-Related Cardiac Risk
    98. Cardiac Arrythmogenesis During Sleep: Mechanisms, Diagnosis and Therapy
    99. Cardiovascular Effects of Sleep-Related Breathing Disorders
    100. Systemic and Pulmonary Hypertension in Obstructive Sleep Apnea
    101. Coronary Artery Disease and Obstructive Sleep Apnea
    102. Heart Failure
    Other Medical Disorders
    103. Sleep and Fatigue in Cancer Patients
    104. Fibromyalgia and Chronic Fatigue Syndrome
    105.Endocrine Disorders
    106. Pain and Sleep Interaction
    107.Gastrointestinal Disorders
    Women’s Health
    108. The Menstrual Cycle and Women’s Sleep and Circadian Rhythms
    109. Pregnancy and Postpartum
    110. Menopause
    Psychiatric Disorders
    111. Anxiety Disorders
    112. Mood Disorders
    113. Schizophrenia
    114. Sleep and Eating Disorders
    115. Medication and Substance Abuse
    116. Monitoring and Staging Human Sleep
    117. Monitoring Techniques for Evaluating Suspected Sleep-disordered Breathing in Adults
    118. Assessment of Sleep-related Erections
    119. Assessment Techniques for Insomnia
    120. Evaluating Sleepiness
    121. Light Therapy
    122..Neurological Monitoring Techniques
    123. Gastrointestinal Monitoring Techniques
    124. Actigraphry
    125. Chronobiological Monitoring Techniques


advert image