Post-Genomic Cardiology book cover

Post-Genomic Cardiology

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach.

This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA.

Hardbound, 944 Pages

Published: June 2014

Imprint: Academic Press

ISBN: 978-0-12-404599-6

Contents

  • Preface
    Section I: BIOCHEMICAL, CELLULAR AND MOLECULAR FUNCTIONING OF THE HEART
    1. Introduction to Post-Genomic Cardiology
    2. Molecular and Biochemical Methodology in the Post-Genomic Era
    3. Cardiovascular Gene Expression. New advances
    4. Cellular Techniques. New advances
    5. Signaling Pathways
    Section II: PEDIATRIC CARDIOLOGY IN THE POST-GENOMIC ERA
    6. Cardiac Development: Molecular and Genetic Analysis
    7. Inherited and Adquired Heart Disease
    Section III: POST-GENOMIC ANALYSIS OF CORONARY ARTERY DISEASE, ANGIOGENESIS AND HYPERTENSION
    8. Molecular Basis of Lipoproteins Disorders, Atherogenesis and Thrombosis
    9. Ischemia and Myocardial Infarction: A Post-Genomic Appraisal
    10.Cellular Pathways and Molecular Events in Cardioprotection
    11. Cardiac Neovascularization: Angiogenesis, Arteriogenesis and Vasculogenesis
    12. Systemic and Pulmonary Hypertension
    Section IV POSTGENOMIC ANALYSIS OF THE MYOCARDIUM
    13. Cardiomyopathies
    14. Heart Response to Inflammation and Infection
    Section V THE FAILING HEART
    15. Molecular analysis of heart failure and remodeling.
    16. Cardiac oxidative stress and cell death in the failing heart (new)
    17. Mitochondrial dynamics in heart failure (new)
    Section VI MOLECULAR AND GENETIC ANALYSIS OF METABOLIC DISORDERS
    18. Fatty Acid and Glucose Metabolism in Cardiac Disease
    Section VII MOLECULAR GENETIC OF DYSRHYTHMIAS
    19. Dysrhythmias and Sudden Death
    Section VIII GENES, GENDER AND ENVIRONMENT
    20. Gender and Cardiovascular Disease
    Section IX AGING AND THE CARDIOVASCULAR SYSTEM
    21. The Aging Heart: Current Post-Genomic Appraisal
    Section X. Current/New approaches to treatment
    22. Genetic and epigenetic therapy of CVDs (new)
    23. Cell transplantation in the broken heart (new)
    Section XI -LOOKING TO THE FUTURE
    23. New and Future trends in Post-Genomic Cardiology. Personalized medicine (new).
    Section XII
    GLOSSARY
    INDEX 

Advertisement

advert image