Pharmacology of Purine and Pyrimidine Receptors

This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors.

Audience
Pharmacologists, immunologists, and biochemists.

Included in series
Advances in Pharmacology

Hardbound, 558 Pages

Published: June 2011

Imprint: Academic Press

ISBN: 978-0-12-385526-8

Contents

    1. The structure of the adenosine receptors: implications for drug discovery
      J. Robert Lane, Veli-Pekka Jaakola, Adriaan P. IJzerman

    2. Adenosine Receptors in Health and Disease
      Stefania Gessi, Stefania Merighi, Katia Varani, and Pier Andrea Borea

    3. Adenosine and the Regulation of Metabolism and Body Temperature
      Bertil Fredholm, Stina M. Johansson and Ying-Qing Wang

    4. Regulation of Leukocyte Function by Adenosine Receptors
      Joel Linden

    5. Role of Adenosine A2B Receptors in Inflammation
      Igor Feoktistov and Italo Biaggioni

    6. Interplay of Hypoxia and A2B Adenosine Receptors in Tissue Protection
      Michael Koeppen, Tobias Eckle, and Holger Eltzschig

    7. Allosteric Modulation of Purine and Pyrimidine Receptors
      Kenneth Jacobson, Zhan-Guo Gao, Aniko Göblyös, and Adriaan IJzerman

    8. Molecular Mechanisms of Purine and Pyrimidine Nucleotide Release
      Eduardo R. Lazarowski, Juliana I. Sesma, Lucia Seminario-Vidal, and Silvia M. Kreda

    9. Impact of Ectoenzymes on Purinergic Signalling
      Filip Kukulski, Sébastien A. Lévesque, and Jean Sévigny

    10. Ectonucleotidases as Regulators of Purinergic Signaling in Inflammation and Thrombosis
      Simon C. Robson and Silvia Deaglio
    11. P2X Receptors in Health and Disease
      Geoffrey Burnstock and Charles Kennedy

    12. Molecular Pharmacology, Physiology, and Structure of the P2Y Receptors
      Ivar von Kügelgen and T. Kendall Harden
    13. P2Y Receptors in Health and Disease
      David Erlinge

    14. P2 Receptor Signaling in Neurons and Glia of the Central Nervous System
      Laszlo Köles Anna Leichsenring, Patrizia Rubini and Peter Illes

    15. Role of Purinergic Receptors in Neuroprotection
      Tozaki-Saitoh Hidetoshi, Makoto Tsuda, and Kazuhide Inoue

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