Pharmacology of 5-HT6 receptors, Part II

The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.
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Audience

Neuroscientists, neurologists, psychologists, psychiatrists, pharmacologists

 

Book information

  • Published: March 2011
  • Imprint: ACADEMIC PRESS
  • ISBN: 978-0-12-385902-0


Table of Contents

  1. The Central Role of 5-HT6 Receptors in Modulating Brain Neurochemistry
    Lee A Dawson
  2. 5-HT6 receptor memory and amnesia. Behavioral Pharmacology: Learning and Memory Processes
    Alfredo Meneses, Pérez-García G, Tellez R, Ponce-Lopez T and C Castillo
  3. Behavioral Pharmacology: Potential Antidepressant and Anxiolytic Properties
    Anna Wesołowska, Magdalena Jastrzębska-Więsek
  4. The 5-Ht6 Receptor as a Target for Developing Novel Anti Obesity Drugs
    David Heal, Jane Gosden, and Sharon Smith
  5. Behavioral and neurochemical pharmacology of 5-HT6 receptors related to reward and reinforcement.
    Gaetano Di Chiara, Valentina Valentini and Sandro Fenu
  6. 5-HT6 Receptor Ligands and their Antipsychotic Potential
    Jørn Arnt and Christina Kurre Olsen
  7. 5-HT6 Receptor Ligands as Antidementia Drugs
    Ellen Siobhan Mitchell